7H-Pyrano(2,3-c)acridin-7-one, 3,12-dihydro-6-hydroxy-3,3-dimethyl-

Base Information Edit

Chemical Name:7H-Pyrano(2,3-c)acridin-7-one, 3,12-dihydro-6-hydroxy-3,3-dimethyl-
CAS No.:13396-93-5
Molecular Formula:C₁₈H₁₅NO₃
Molecular Weight:293.322
Hs Code.:2934999090
DSSTox Substance ID:DTXSID20158436
Nikkaji Number:J14.916K
Wikidata:Q83026700
Metabolomics Workbench ID:135333
ChEMBL ID:CHEMBL454569
Mol file:13396-93-5.mol

Synonyms:13396-93-5;7H-Pyrano(2,3-c)acridin-7-one, 3,12-dihydro-6-hydroxy-3,3-dimethyl-;6-hydroxy-3,3-dimethyl-12H-pyrano[2,3-c]acridin-7-one;3,3-Dimethyl-6-hydroxy-3,12-dihydroxy-7H-pyrano(2,3-c)acridin-7-one;De-N-methylnoracronycine;des-N-methylnoracronycine;Des-N-methyl-noracronycine;CHEMBL454569;DTXSID20158436;RPWNPBFZWFWZNJ-UHFFFAOYSA-N;6-hydroxy-3,3-dimethyl-3,12-dihydro-7h-pyrano[3,2-h]acridin-7-one

Suppliers and Price of 7H-Pyrano(2,3-c)acridin-7-one, 3,12-dihydro-6-hydroxy-3,3-dimethyl-

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 7H-Pyrano(2,3-c)acridin-7-one, 3,12-dihydro-6-hydroxy-3,3-dimethyl- Edit

Chemical Property:

Vapor Pressure:1.63E-10mmHg at 25°C
Boiling Point:497.4°Cat760mmHg
Flash Point:254.6°C
PSA：62.32000
Density:1.294g/cm³
LogP:3.57110
XLogP3:4.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:293.10519334
Heavy Atom Count:22
Complexity:501

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C=CC2=C(O1)C=C(C3=C2NC4=CC=CC=C4C3=O)O)C

Technology Process of 7H-Pyrano(2,3-c)acridin-7-one, 3,12-dihydro-6-hydroxy-3,3-dimethyl-

There total 27 articles about 7H-Pyrano(2,3-c)acridin-7-one, 3,12-dihydro-6-hydroxy-3,3-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 107-86-8
3,3-dimethyl acrylaldehyde

: 20324-10-1
1,3-dihydroxyacridin-9(10H)-one

: 13396-93-5
6-Hydroxy-3,3-dimethyl-3,12-dihydro-7H-pyrano<2,3-c>acridin-7-one

Guidance literature:: With ethylenediaminediacetic acid; In tetrahydrofuran; for 8h; Inert atmosphere; Reflux;
DOI:10.5012/bkcs.2010.31.8.2406

Reference yield: 52.0%

: 132456-30-5
4-(3'-methyl-2'-butenyl)-1,3-dihydroxy-9-acridone

: 13396-93-5
6-Hydroxy-3,3-dimethyl-3,12-dihydro-7H-pyrano<2,3-c>acridin-7-one

Guidance literature:: With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In toluene; for 14h; Heating;

Reference yield:

: 115-18-4
2-methyl-3-buten-2-ol

: 13396-93-5
6-Hydroxy-3,3-dimethyl-3,12-dihydro-7H-pyrano<2,3-c>acridin-7-one

Guidance literature:: Multi-step reaction with 6 steps

1: 92 percent / BF₃*Et₂O / dioxane / Heating

2: H₂O, alkali

3: 94 percent / Cu(OAc)2 / propan-2-ol

4: 91 percent / PPE

5: EtSNa / dimethylformamide

6: DDQ / 1,2-dichloro-benzene

With copper diacetate; boron trifluoride diethyl etherate; water; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium thioethylate; In 1,4-dioxane; N,N-dimethyl-formamide; 1,2-dichloro-benzene; isopropyl alcohol;
DOI:10.1039/cc9960000199