2,3,4,5,6-PENTAMETHYLBENZOPHENONE

Base Information

• Chemical Name: 2,3,4,5,6-PENTAMETHYLBENZOPHENONE
• CAS No.: 20386-33-8
• Molecular Formula: C18H20 O
• Molecular Weight: 252.356
• Hs Code.: 2914399090
• Mol file: 20386-33-8.mol

Synonyms:Benzophenone,2,3,4,5,6-pentamethyl- (6CI,8CI); 2,3,4,5,6-Pentamethylbenzophenone; Phenyl2,3,4,5,6-pentamethylphenyl ketone

Chemical Property of 2,3,4,5,6-PENTAMETHYLBENZOPHENONE

Chemical Property:

• Vapor Pressure: 5.27E-06mmHg at 25°C
• Melting Point: 135-137 °C(lit.)
• Boiling Point: 380.9°Cat760mmHg
• Flash Point: 163.8°C
• PSA: 17.07000
• Density: 1.013g/cm³
• LogP: 4.45960

Purity/Quality:

98%min ^*data from raw suppliers

2,3,4,5,6-PENTAMETHYLBENZOPHENONE Aldrich ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3,4,5,6-PENTAMETHYLBENZOPHENONE

There total 18 articles about 2,3,4,5,6-PENTAMETHYLBENZOPHENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

→ 2,3,4,5,6-Pentamethylbenzophenone (20386-33-8)

Guidance literature:

With 8,8′-biquinoline; palladium diacetate; In water; dimethyl sulfoxide; at 80 ℃; for 6h; Inert atmosphere;

Reference yield: 83.0%

pentamethylphenylglyoxylic acid + phenylboronic acid (98-80-6) → 2,3,4,5,6-Pentamethylbenzophenone (20386-33-8)

Guidance literature:

With silver carbonate; In acetonitrile; at 60 ℃; for 1h;

DOI:10.1039/c4ra04361h

Reference yield: 83.0%

Benzoyl bromide (618-32-6) + pentamethylbenzene, (700-12-9) → 2,3,4,5,6-Pentamethylbenzophenone (20386-33-8)

Guidance literature:

With pyrographite; In benzene; for 3h; Heating;

DOI:10.1039/a703947f

upstream raw materials:

pentamethylbenzene,

benzoyl chloride

2',3',4',5',6'-pentamethylacetophenone

Hexamethylbenzene

Downstream raw materials:

trideuterioacetylpentamethylbenzene

4-Methoxybenzophenone

ortho-methoxybenzophenone

pentamethylbenzene,

Refernces

• 1、 -. "Method for preparing aromatic ketone in aqueous phase". Paragraph 0046-0049. . Retrieved 2018/04/26.
• 2、 Chang, Sheng,Wang, Jian Feng,Dong, Lin Lin,Wang, Dan,Feng, Bo,Shi, Yuan Tai. "Ag(i)/persulfate-catalyzed decarboxylative coupling of α-oxocarboxylates with organotrifluoroborates in water under room temperature". . p. 51928 - 51934. Retrieved 2017/11/22.