2,2-Dimethyl-4-(1-oxidopyridin-1-ium-2-yl)-3,4-dihydrochromene-6-carbonitrile

Base Information

Chemical Name:2,2-Dimethyl-4-(1-oxidopyridin-1-ium-2-yl)-3,4-dihydrochromene-6-carbonitrile
CAS No.:120280-33-3
Molecular Formula:C₁₇H₁₆N₂O₂
Molecular Weight:280.326
Hs Code.:
Nikkaji Number:J367.064C
Mol file:120280-33-3.mol

Synonyms:Ro 31-7837;Ro 31-7837, (+-)-isomer;Ro-31-7837

Suppliers and Price of 2,2-Dimethyl-4-(1-oxidopyridin-1-ium-2-yl)-3,4-dihydrochromene-6-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2,2-Dimethyl-4-(1-oxidopyridin-1-ium-2-yl)-3,4-dihydrochromene-6-carbonitrile

Chemical Property:

Vapor Pressure:3.43E-09mmHg at 25°C
Boiling Point:475.1°C at 760 mmHg
Flash Point:241.1°C
PSA：58.48000
Density:1.18g/cm³
LogP:3.67978
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:280.121177757
Heavy Atom Count:21
Complexity:428

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CC(C2=C(O1)C=CC(=C2)C#N)C3=CC=CC=[N+]3[O-])C

Technology Process of 2,2-Dimethyl-4-(1-oxidopyridin-1-ium-2-yl)-3,4-dihydrochromene-6-carbonitrile

There total 8 articles about 2,2-Dimethyl-4-(1-oxidopyridin-1-ium-2-yl)-3,4-dihydrochromene-6-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 120281-06-3
3,4-dihydro-2,2-dimethyl-4-(pyridin-2-yl)-2H-1-benzopyran-6-carbonitrile

: 120280-33-3,120280-90-2,120280-91-3
2-(6-cyano-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)pyridine N-oxide

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane;

Reference yield:

: 120281-06-3
3,4-dihydro-2,2-dimethyl-4-(pyridin-2-yl)-2H-1-benzopyran-6-carbonitrile

: 10420-89-0
(S)-1-(1-Naphthyl)ethylamine

: 120280-33-3,120280-90-2,120280-91-3
2-(6-cyano-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)pyridine N-oxide

: 120281-17-6,120281-63-2,120281-66-5
3,4-dihydro-2,2-dimethyl-4-(pyridin-2-yl)-2H-1-benzopyran-6-carboxylic acid

Guidance literature:: In diethyl ether; ethanol; acetone;

Reference yield:

: 5029-67-4
2-iodopyridine

: 120280-33-3,120280-90-2,120280-91-3
2-(6-cyano-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)pyridine N-oxide

Guidance literature:: Multi-step reaction with 4 steps

1: triphenylphosphine / palladium(II) chloride; copper(I) iodide / water; ethyl acetate; diethylamine; Petroleum ether

2: ethyl acetate; 1,2-dichloro-benzene; Petroleum ether

3: palladium / ethanol; ethyl acetate; Petroleum ether

4: diethyl ether; ethanol

With triphenylphosphine; palladium(II) chloride; copper(I) iodide; palladium; In diethyl ether; ethanol; water; ethyl acetate; diethylamine; 1,2-dichloro-benzene; Petroleum ether;