2,3-Piperazinedione, 1-(p-((5-amino-2-pyridyl)amino)benzyl)-4-benzyl-

Base Information

Chemical Name:2,3-Piperazinedione, 1-(p-((5-amino-2-pyridyl)amino)benzyl)-4-benzyl-
CAS No.:77917-05-6
Molecular Formula:C₂₃H₂₃N₅O₂
Molecular Weight:401.468
Hs Code.:
DSSTox Substance ID:DTXSID10228551
Nikkaji Number:J117.813J
Wikidata:Q83108544
Mol file:77917-05-6.mol

Synonyms:77917-05-6;BRN 5648671;2,3-Piperazinedione, 1-(p-((5-amino-2-pyridyl)amino)benzyl)-4-benzyl-;1-(4-(5-Amino-2-pyridyl)aminobenzyl)-4-benzyl-2,3-dioxopiperazine;SCHEMBL11052061;DTXSID10228551;LS-111849;1-[4-[(5-Amino-2-pyridinyl)amino]benzyl]-4-benzyl-2,3-piperazinedione;1-[[4-[(5-AMINOPYRIDIN-2-YL)AMINO]PHENYL]METHYL]-4-BENZYL-PIPERAZINE-2,3-DIONE

Suppliers and Price of 2,3-Piperazinedione, 1-(p-((5-amino-2-pyridyl)amino)benzyl)-4-benzyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,3-Piperazinedione, 1-(p-((5-amino-2-pyridyl)amino)benzyl)-4-benzyl-

Chemical Property:

Vapor Pressure:3.52E-16mmHg at 25°C
Melting Point:154-155 °C
Boiling Point:638.1°C at 760 mmHg
PKA:6.30±0.10(Predicted)
Flash Point:339.7°C
PSA：91.56000
Density:1.339g/cm³
LogP:3.30840
XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:401.18517499
Heavy Atom Count:30
Complexity:586

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(C(=O)C(=O)N1CC2=CC=CC=C2)CC3=CC=C(C=C3)NC4=NC=C(C=C4)N

Technology Process of 2,3-Piperazinedione, 1-(p-((5-amino-2-pyridyl)amino)benzyl)-4-benzyl-

There total 4 articles about 2,3-Piperazinedione, 1-(p-((5-amino-2-pyridyl)amino)benzyl)-4-benzyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.3%

: 77939-47-0
1-benzyl-4-[4-N-(5-nitro-2-pyridyl)aminobenzyl]-2,3-dioxopiperazine

: 77917-05-6
1-<4-(5-amino-2-pyridyl)aminobenzyl>-4-benzyl-2,3-dioxopiperazine

Guidance literature:: With hydrogenchloride; iron; ice cooling, 15 min, then 1 h, 30 - 40 deg C;
DOI:10.1248/cpb.29.1594

Reference yield: 86.0%

: 77917-05-6
1-<4-(5-amino-2-pyridyl)aminobenzyl>-4-benzyl-2,3-dioxopiperazine

Guidance literature:

Reference yield:

: 4548-45-2
2-chloro-5-nitropyridine

: 77917-05-6
1-<4-(5-amino-2-pyridyl)aminobenzyl>-4-benzyl-2,3-dioxopiperazine

Guidance literature:: Multi-step reaction with 2 steps

2: 86 percent / H₂ / 5 percent Pd-C / acetic acid / Ambient temperature; reduction between var. conditions

With hydrogen; palladium on activated charcoal; In acetic acid;
DOI:10.1248/cpb.29.1594