Chemical Property of N-Methylprotoporphyrin
Chemical Property:
- PSA:120.04000
- Density:1.25g/cm3
- LogP:4.05100
- XLogP3:4.6
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:6
- Rotatable Bond Count:8
- Exact Mass:576.27365564
- Heavy Atom Count:43
- Complexity:1040
- Purity/Quality:
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97% *data from raw suppliers
N-Methylprotoporphyrin *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CC1=C(C2=CC3=NC(=CC4=NC(=CC5=C(C(=C(N5C)C=C1N2)C=C)C)C(=C4CCC(=O)O)C)C(=C3C)CCC(=O)O)C=C
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Description
N-methyl Protoporphyrin IX is a transition state analog that potently inhibits protoporphyrin IX ferrochelatase (Ki = 10 nM), blocking the terminal step of the heme biosynthetic pathway. It is used to study the effect of heme synthesis blockade in cell systems.