15-Oxoprostaglandin E1

Base Information

Chemical Name:15-Oxoprostaglandin E1
CAS No.:22973-19-9
Molecular Formula:C₂₀H₃₂O₅
Molecular Weight:352.471
Hs Code.:
European Community (EC) Number:682-024-7
UNII:63FR527UJ6
DSSTox Substance ID:DTXSID601216545
Metabolomics Workbench ID:2488
Nikkaji Number:J363.760C
Wikidata:Q27098096
Mol file:22973-19-9.mol

Synonyms:15-keto PGE1;15-keto-PGE;15-ketoprostaglandin E;15-ketoprostaglandin E, (11alpha,13E)-(+-)-isomer;15-ketoprostaglandin E, (5Z,11alpha)-isomer, 2H-labeled;15-ketoprostaglandin E1

Suppliers and Price of 15-Oxoprostaglandin E1

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
15-Keto Prostaglandin E1
500ug
$ 319.00

TRC
15-KetoProstaglandinE1
1mg
$ 225.00

Medical Isotopes, Inc.
15-KetoprostaglandinE1
5 mg
$ 2400.00

Medical Isotopes, Inc.
15-KetoprostaglandinE1
1 mg
$ 925.00

Cayman Chemical
15-keto Prostaglandin E1 ≥98%
1mg
$ 99.00

Cayman Chemical
15-keto Prostaglandin E1 ≥98%
500μg
$ 52.00

Cayman Chemical
15-keto Prostaglandin E1 ≥98%
10mg
$ 728.00

Cayman Chemical
15-keto Prostaglandin E1 ≥98%
5mg
$ 416.00

American Custom Chemicals Corporation
15-KETOPROSTAGLANDIN E1 95.00%
0.5MG
$ 825.00

American Custom Chemicals Corporation
15-KETOPROSTAGLANDIN E1 95.00%
5MG
$ 3025.00

Total 14 raw suppliers

Chemical Property of 15-Oxoprostaglandin E1

Chemical Property:

Vapor Pressure:1.32E-13mmHg at 25°C
Boiling Point:533.4 °C at 760 mmHg
PKA:4.77±0.10(Predicted)
Flash Point:290.5 °C
PSA：91.67000
Density:1.128 g/cm₃
LogP:3.68330
Storage Temp.:-20?C Freezer
Solubility.:Chloroform (Slightly), Methanol (Soluble)
XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:13
Exact Mass:352.22497412
Heavy Atom Count:25
Complexity:469

Purity/Quality:

99% ^*data from raw suppliers

15-Keto Prostaglandin E1 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCC(=O)C=CC1C(CC(=O)C1CCCCCCC(=O)O)O
Isomeric SMILES:CCCCCC(=O)/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1CCCCCCC(=O)O)O
Uses 15-keto PGE1 is the inactive metabolite of PGE1 produced by 15-hydroxy PGDH. It has greatly diminished biological activity compared to PGE1. Alprostadil impurity C.

Technology Process of 15-Oxoprostaglandin E1

There total 10 articles about 15-Oxoprostaglandin E1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 35851-49-1
14-Phenyl-9,12-dioxo-11-hydroxytetradec-13-en-carbonsaeure

: 22973-19-9,28312-76-7
11α-Hydroxy-9,15-dioxo-13-prostensaeure

Guidance literature:: Multi-step reaction with 3 steps

1: OH^-

2: NaIO₄, OsO₄

3: (i) Zn, (ii) /BRN= 2947272/

With sodium periodate; osmium(VIII) oxide; hydroxide;
DOI:10.1016/S0040-4039(01)87960-0

Reference yield:

: 22935-06-4
2-(6-Carboxy-hexyl)-3-styryl-4-hydroxy-cyclopenten-⁽²⁾-on-⁽¹⁾

: 22973-19-9,28312-76-7
11α-Hydroxy-9,15-dioxo-13-prostensaeure

Guidance literature:: Multi-step reaction with 2 steps

1: NaIO₄, OsO₄

2: (i) Zn, (ii) /BRN= 2947272/

With sodium periodate; osmium(VIII) oxide;
DOI:10.1016/S0040-4039(01)87960-0

Reference yield:

: 3-Oxo-undecan-1,11-disaeure

: 22973-19-9,28312-76-7
11α-Hydroxy-9,15-dioxo-13-prostensaeure

Guidance literature:: Multi-step reaction with 4 steps

2: OH^-

3: NaIO₄, OsO₄

4: (i) Zn, (ii) /BRN= 2947272/

With sodium periodate; osmium(VIII) oxide; hydroxide;
DOI:10.1016/S0040-4039(01)87960-0