Sulforidazine

Base Information

Chemical Name:Sulforidazine
CAS No.:14759-06-9
Molecular Formula:C21H26 N2 O2 S2
Molecular Weight:402.582
Hs Code.:2934300000
European Community (EC) Number:238-818-7
UNII:B7599I244X
DSSTox Substance ID:DTXSID30864531
Nikkaji Number:J8.517K
Wikipedia:Sulforidazine
Wikidata:Q7636215
NCI Thesaurus Code:C84185
Metabolomics Workbench ID:49696
ChEMBL ID:CHEMBL2107268
Mol file:14759-06-9.mol

Synonyms:sulforidazine

Suppliers and Price of Sulforidazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Thioridazine2-Sulfone
50mg
$ 1455.00

American Custom Chemicals Corporation
SULFORIDAZINE 95.00%
5MG
$ 345.40

aablocks
10H-Phenothiazine,10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)-
50mg
$ 1470.00

aablocks
10H-Phenothiazine,10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfonyl)-
5mg
$ 315.00

Total 12 raw suppliers

Chemical Property of Sulforidazine

Chemical Property:

Vapor Pressure:7.45E-14mmHg at 25°C
Melting Point:121-123°
Boiling Point:589.1°Cat760mmHg
PKA:9.83±0.10(Predicted)
Flash Point:310.1°C
PSA：74.30000
Density:1.221g/cm³
LogP:5.65090
Storage Temp.:Refrigerator, Under Inert Atmosphere
Solubility.:Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:402.14357042
Heavy Atom Count:27
Complexity:606

Purity/Quality:

98%Min ^*data from raw suppliers

Thioridazine2-Sulfone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)S(=O)(=O)C
Uses A major metabolite of Thioridazine (THD 2-SO2). Thioridazine 2-Sulfone (Thioridazine EP Impurity E) is a major metabolite of Thioridazine (THD 2-SO2).
Therapeutic Function Neuroleptic

Technology Process of Sulforidazine

There total 4 articles about Sulforidazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 5588-33-0
mesoridazine

: 14759-06-9
sulforidazine

Guidance literature:: With potassium permanganate; In acetone; at 45 ℃;
DOI:10.1002/hlca.200590089

Reference yield:

: 32672-69-8
mesoridazine besylate

: 14759-06-9
sulforidazine

: C₂₁H₂₆N₂OS

: C₂₀H₂₄N₂OS₂

: C₂₁H₂₆N₂O₂S₂

: C₂₁H₂₆N₂O₂S₂

: 50-52-2,52496-67-0,57129-06-3,114488-10-7
thioridazine

Guidance literature:: at 20 ℃; for 4.26667h; pH=7; Kinetics; Quantum yield; Photolysis;
DOI:10.1016/j.scitotenv.2017.08.040

Reference yield:

: 50-52-2,52496-67-0,57129-06-3,114488-10-7
thioridazine

: 14759-06-9
sulforidazine

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / aq. H₂O₂; TiCl₃; AlCl₃ / methanol / 0.08 h / 20 °C

2: 52 percent / aq. KMnO₄ / acetone / 45 °C

With potassium permanganate; aluminium trichloride; titanium(III) chloride; dihydrogen peroxide; In methanol; acetone;
DOI:10.1002/hlca.200590089