1,2,4-Triazin-3(2H)-one, 5-phenyl- (9CI)

Base Information

• Chemical Name: 1,2,4-Triazin-3(2H)-one, 5-phenyl- (9CI)
• CAS No.: 31952-61-1
• Molecular Formula: C9H7 N3 O
• Molecular Weight: 173.174
• Hs Code.: 2933699090
• Mol file: 31952-61-1.mol

Synonyms:as-Triazin-3(2H)-one,5-phenyl- (6CI); as-Triazin-3-ol, 5-phenyl- (8CI); 5-Phenyl-1,2,4-triazin-3-one

Chemical Property of 1,2,4-Triazin-3(2H)-one, 5-phenyl- (9CI)

Chemical Property:

• Vapor Pressure: 1.27E-08mmHg at 25°C
• Boiling Point: 447.4°Cat760mmHg
• PKA: 10.48±0.40(Predicted)
• Flash Point: 224.4°C
• PSA: 58.90000
• Density: 1.31g/cm³
• LogP: 1.24420

Purity/Quality:

99% ^*data from raw suppliers

5-PHENYL-[1,2,4]TRIAZIN-3-OL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2,4-Triazin-3(2H)-one, 5-phenyl- (9CI)

There total 8 articles about 1,2,4-Triazin-3(2H)-one, 5-phenyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

3-methoxy-5-phenyl-1,2,4-triazine (28735-28-6) → 5-phenyl-1,2,4-triazin-3(2H)-one (31952-61-1) + 5-phenyl-1,2,4-triazin-3-amine (942-60-9) + 2-methyl-5-phenyl-1,2,4-triazin-3(2H)-one (31947-28-1) + 3-methylamino-5-phenyl-1,2,4-triazine

Guidance literature:

With ammonia; In ethanol; at 150 ℃; for 24h;

Reference yield: 31.0%

phenyllithium (591-51-5) + 3,5-bis(trimethylsilyloxy)-1,2,4-triazine (17331-61-2) → 5-phenyl-1,2,4-triazin-3(2H)-one (31952-61-1) + 6-phenyl-[1,2,4]triazinane-3,5-dione

Guidance literature:

With triethyl borate; In tetrahydrofuran; at -100 - 20 ℃; for 3.5h;

DOI:10.1039/b205058g

Reference yield:

→ 5-phenyl-1,2,4-triazin-3(2H)-one (31952-61-1)

Guidance literature:

With sodium hydroxide;

upstream raw materials:

5-phenyl-1,2,4-triazin-3-amine

3-methoxy-5-phenyl-1,2,4-triazine

phenyllithium

3,5-bis(trimethylsilyloxy)-1,2,4-triazine

Downstream raw materials:

2-benzyl-5-phenyl-1,2,4-triazin-3(2H)-one

2-benzyl-5-phenyl-4,5-dihydro-1,2,4-triazin-3(2H)-one

5-phenyl-1,2,4-triazin-3-amine

3-chloro-5-phenyl-1,2,4-triazine