2-Piperidinoethyl=o-(propylthio)benzoate

Base Information

• Chemical Name: 2-Piperidinoethyl=o-(propylthio)benzoate
• CAS No.: 67031-81-6
• Molecular Formula: C₁₇H₂₅NO₂S
• Molecular Weight: 307.457
• Mol file: 67031-81-6.mol

Synonyms:o-(Propylthio)benzoic acid 2-piperidinoethyl ester;BENZOIC ACID,o-(PROPYLTHIO)-,2-PIPERIDINOETHYL ESTER;

Chemical Property of 2-Piperidinoethyl=o-(propylthio)benzoate

Chemical Property:

• Vapor Pressure: 8.58E-08mmHg at 25°C
• Boiling Point: 435.7°Cat760mmHg
• Flash Point: 217.3°C
• PSA: 54.84000
• Density: 1.11g/cm³
• LogP: 3.76930

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Piperidinoethyl=o-(propylthio)benzoate

There total 3 articles about 2-Piperidinoethyl=o-(propylthio)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S-propyl)-2-thiosalicylic acid (21213-10-5) → 2-propylmercapto-benzoic acid-(2-piperidino-ethyl ester) (67031-81-6)

Guidance literature:

Multi-step reaction with 2 steps

1: phosphorus (V)-chloride

2: diethyl ether; pyridine

With pyridine; diethyl ether; phosphorus pentachloride;

DOI:10.1021/ja01858a063

Reference yield:

anthranilic acid (118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4) → 2-propylmercapto-benzoic acid-(2-piperidino-ethyl ester) (67031-81-6)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium nitrite; aqueous hydrochloric acid / Reaktion ueber mehrere Stufen

2: phosphorus (V)-chloride

3: diethyl ether; pyridine

With pyridine; hydrogenchloride; diethyl ether; phosphorus pentachloride; sodium nitrite;

DOI:10.1021/ja01858a063

Reference yield:

1-piperidinoethanol (3040-44-6) + 2-propylsulfanyl-benzoyl chloride (473742-08-4) → 2-propylmercapto-benzoic acid-(2-piperidino-ethyl ester) (67031-81-6)

Guidance literature:

With pyridine; diethyl ether;

DOI:10.1021/ja01858a063

upstream raw materials:

1-piperidinoethanol

2-propylsulfanyl-benzoyl chloride

(S-propyl)-2-thiosalicylic acid

anthranilic acid