20-(Hydroxyimino)pregna-5,16-dien-3-yl acetate

Base Information

Chemical Name:20-(Hydroxyimino)pregna-5,16-dien-3-yl acetate
CAS No.:2174-13-2
Molecular Formula:C₂₃H₃₃NO₃
Molecular Weight:371.52
Hs Code.:
European Community (EC) Number:218-530-8
DSSTox Substance ID:DTXSID80944352
Mol file:2174-13-2.mol

Synonyms:2174-13-2;DTXSID80944352;FT-0634092;20-(Hydroxyimino)pregna-5,16-dien-3-yl acetate

Suppliers and Price of 20-(Hydroxyimino)pregna-5,16-dien-3-yl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Pregnenolone-16-ene Acetate Oxime
1g
$ 425.00

TRC
Pregnenolone-16-eneAcetateOxime
10g
$ 1210.00

Medical Isotopes, Inc.
Abirateronerelatedcompound3
5 g
$ 990.00

American Custom Chemicals Corporation
16-DEHYDROPREGNENOLONE ACETATE OXIME 95.00%
5G
$ 885.31

American Custom Chemicals Corporation
16-DEHYDROPREGNENOLONE ACETATE OXIME 95.00%
1G
$ 630.63

AHH
16-Dehydropregnenoloneacetateoxime 98%
50g
$ 412.00

Total 18 raw suppliers

Chemical Property of 20-(Hydroxyimino)pregna-5,16-dien-3-yl acetate

Chemical Property:

Vapor Pressure:7.12E-12mmHg at 25°C
Melting Point:220-223 °C
Boiling Point:495°Cat760mmHg
PKA:12.13±0.10(Predicted)
Flash Point:253.2°C
PSA：58.89000
Density:1.23g/cm³
LogP:5.26730
Storage Temp.:-20°C
Solubility.:Chloroform (Slightly), Ethyl Acetate
XLogP3:4.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:371.24604391
Heavy Atom Count:27
Complexity:736

Purity/Quality:

98%min ^*data from raw suppliers

Pregnenolone-16-ene Acetate Oxime ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=NO)C1=CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC(=O)C)C)C
Uses Pregnenolone-16-ene Acetate Oxime is used in the synthesis of pegnange derivatives as antioxidant and anti-dyslipidemic agents.

Technology Process of 20-(Hydroxyimino)pregna-5,16-dien-3-yl acetate

There total 9 articles about 20-(Hydroxyimino)pregna-5,16-dien-3-yl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 979-02-2
16-dehydropregnenolone acetate

: 23549-24-8,23549-26-0,2174-13-2
3β-acetoxy-20-hydroxyiminopregna-5,16-diene

Guidance literature:: With pyridine; hydroxylamine hydrochloride; In ethanol; for 0.5h; Reflux;
DOI:10.1021/acs.orglett.8b01783

Reference yield:

: 512-04-9
diosgenin

: 23549-24-8,23549-26-0,2174-13-2
3β-acetoxy-20-hydroxyiminopregna-5,16-diene

Guidance literature:: Multi-step reaction with 2 steps

1.1: NH₄Cl / pyridine / Heating

1.2: CrO₃; CH₃COOH / 1,2-dichloro-ethane / 0 °C

1.3: AcONa*3H₂O / Heating

2.1: 87 percent / NH₂OH*HCl / pyridine; ethanol; H₂O / 0.5 h / Heating

With hydroxylamine hydrochloride; ammonium chloride; In pyridine; ethanol; water;
DOI:10.1016/j.steroids.2005.07.006

Reference yield:

: 212952-62-0
(25S)-3β,26-diacetoxy-furosta-5,20(22)-diene

: 23549-24-8,23549-26-0,2174-13-2
3β-acetoxy-20-hydroxyiminopregna-5,16-diene

Guidance literature:: Multi-step reaction with 3 steps

1: acetic anhydride; acetic acid; chromium(VI) oxide / water / 6 h / 0 - 20 °C

2: sodium acetate / water / 3 h / Reflux

3: hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine / ethanol / 1.5 h / Reflux

With chromium(VI) oxide; hydroxylamine hydrochloride; sodium acetate; acetic anhydride; acetic acid; N-ethyl-N,N-diisopropylamine; In ethanol; water;