Coccinine, (+/-)-

Base Information

Chemical Name:Coccinine, (+/-)-
CAS No.:485-57-4
Molecular Formula:C₁₇H₁₉NO₄
Molecular Weight:301.342
Hs Code.:
UNII:84264F9JYT,3SRR5RK902
Nikkaji Number:J13.095H
Wikidata:Q105166327
Mol file:485-57-4.mol

Synonyms:(+/-)-Coccinine;Coccinine, (+/-)-;Coccinine;3SRR5RK902;Coccinine, (-)-;O2-Methyl-2-epipancracine;UNII-3SRR5RK902;84264F9JYT;485-57-4;Pancracine, O2-methyl-, (2beta)-(+/-)-;139068-98-7;6,11-Methano-6H-benzo(b)-1,3-benzodioxolo(5,6-E)azepin-8-ol, 5,6a,7,8,9,11-hexahydro-9-methoxy-, (6R,6aS,8S,9R,11S)-rel-;6,11-Methano-6H-1,3-benzodioxolo(5,6-C)(1)benzazepin-8-ol, 5,6a,7,8,9,11-hexahydro-9-methoxy-, (6alpha,6abeta,8beta,9beta,11alpha)-;6,11-Methano-6H-benzo(b)-1,3-benzodioxolo(5,6-E)azepin-8-ol, 5,6a,7,8,9,11-hexahydro-9-methoxy-, (6R,6aS,8S,9R,11S)-;Pancracine, O2-methyl-, (2.beta.)-;O2-methyl-2beta-pancracine;UNII-84264F9JYT;Pancracine, O2-methyl-, (2beta)-;O2-METHYL-2.BETA.-PANCRACINE;PANCRACINE, O2-METHYL-, (2.BETA.)-(+/-)-;6,11-METHANO-6H-1,3-BENZODIOXOLO(5,6-C)(1)BENZAZEPIN-8-OL, 5,6A,7,8,9,11-HEXAHYDRO-9-METHOXY-, (6.ALPHA.,6A.BETA.,8.BETA.,9.BETA.,11.ALPHA.)-;6,11-METHANO-6H-1,3-BENZODIOXOLO(5,6-C)(1)BENZAZEPIN-8-OL, 5,6A,7,8,9,11-HEXAHYDRO-9-METHOXY-, (6R-(6.ALPHA.,6A.BETA.,8.BETA.,9.BETA.,11.ALPHA.))-;6,11-Methano-6H-1,3-benzodioxolo(5,6-C)(1)benzazepin-8-ol, 5,6a,7,8,9,11-hexahydro-9-methoxy-, (6R-(6alpha,6abeta,8beta,9beta,11alpha))-

Suppliers and Price of Coccinine, (+/-)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Coccinine, (+/-)-

Chemical Property:

XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:301.13140809
Heavy Atom Count:22
Complexity:495

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1C=C2C(CC1O)N3CC2C4=CC5=C(C=C4C3)OCO5
Isomeric SMILES:CO[C@@H]1C=C2[C@H](C[C@@H]1O)N3C[C@H]2C4=CC5=C(C=C4C3)OCO5

Technology Process of Coccinine, (+/-)-

There total 93 articles about Coccinine, (+/-)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 139025-49-3,144609-93-8
(+/-)-O-benzylcoccinine

: 485-57-4,642-52-4,43208-82-8,98632-48-5,139068-98-7,139068-99-8
(+/-)-coccinine

Guidance literature:: With trimethylsilyl iodide; In chloroform;
DOI:10.1016/0040-4039(91)85045-7

Reference yield: 86.7%

: 139025-49-3,144609-93-8
(+/-)-O-benzylcoccinine

: 485-57-4,642-52-4,43208-82-8,98632-48-5,139068-98-7,139068-99-8
(+/-)-coccinine

Guidance literature:: With trimethylsilyl iodide; In chloroform; for 5h; Ambient temperature;
DOI:10.1021/jo00052a051

Reference yield: 51.0%

: 191787-73-2
C₁₈H₂₁NO₅

: 642-52-4
(-)-montanine

: 485-57-4
(-)-coccinine

Guidance literature:: With diisobutylaluminium hydride; In hexane; dichloromethane; at 0 - 30 ℃; for 19h; enantioselective reaction;
DOI:10.1002/anie.201307324