2-(2,6-dimethyl-1-propadienylpyridin-4(1H)-ylidene)-1H-indene-1,3(2H)-dione

Base Information

• Chemical Name: 2-(2,6-dimethyl-1-propadienylpyridin-4(1H)-ylidene)-1H-indene-1,3(2H)-dione
• CAS No.: 80672-64-6
• Molecular Formula: C₁₉H₁₅NO₂
• Molecular Weight: 289.334
• Mol file: 80672-64-6.mol

Synonyms:1H-Indene-1,3(2H)-dione,2-[2,6-dimethyl-1-(1,2-propadienyl)-4(1H)-pyridinylidene]- (9CI); NSC 367266

Chemical Property of 2-(2,6-dimethyl-1-propadienylpyridin-4(1H)-ylidene)-1H-indene-1,3(2H)-dione

Chemical Property:

• Vapor Pressure: 7.95E-07mmHg at 25°C
• Boiling Point: 406.7°Cat760mmHg
• Flash Point: 169.6°C
• Density: 1.255g/cm³

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(2,6-dimethyl-1-propadienylpyridin-4(1H)-ylidene)-1H-indene-1,3(2H)-dione

There total 3 articles about 2-(2,6-dimethyl-1-propadienylpyridin-4(1H)-ylidene)-1H-indene-1,3(2H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

2-(2,6-dimethyl-4H-pyran-4-ylidene)-1H-indene-1,3(2H)-dione (71107-31-8) + prop-2-yn-1-amine hydrochloride (15430-52-1) → 2-(2,6-Dimethyl-1-propa-1,2-dienyl-1H-pyridin-4-ylidene)-indan-1,3-dione (80672-64-6) + -2 indanedione-1,3 (80672-63-5)

Guidance literature:

With potassium carbonate; In acetonitrile; for 72h; Heating;

Reference yield:

2,6-dimethylpyrone (1004-36-0) → 2-(2,6-Dimethyl-1-propa-1,2-dienyl-1H-pyridin-4-ylidene)-indan-1,3-dione (80672-64-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 69.8 percent / acetic anhydride / 8 h / Heating

2: 10 percent / potassium carbonate / acetonitrile / 72 h / Heating

With potassium carbonate; In acetic anhydride; acetonitrile;

Reference yield:

1H-indene-1,3(2H)-dione (606-23-5) → 2-(2,6-Dimethyl-1-propa-1,2-dienyl-1H-pyridin-4-ylidene)-indan-1,3-dione (80672-64-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 69.8 percent / acetic anhydride / 8 h / Heating

2: 10 percent / potassium carbonate / acetonitrile / 72 h / Heating

With potassium carbonate; In acetic anhydride; acetonitrile;

upstream raw materials:

2-(2,6-dimethyl-4H-pyran-4-ylidene)-1H-indene-1,3(2H)-dione

prop-2-yn-1-amine hydrochloride

2,6-dimethylpyrone

1H-indene-1,3(2H)-dione