argipressin, (4-azido)Phe(3)-

Base Information

• Chemical Name: argipressin, (4-azido)Phe(3)-
• CAS No.: 97474-07-2
• Molecular Formula: C₄₆H₆₄N₁₈O₁₂S₂
• Molecular Weight: 1125.26
• Mol file: 97474-07-2.mol

Synonyms:1,2-Dithia-5,8,11,14,17-pentaazacycloeicosane,cyclic peptide deriv.

Chemical Property of argipressin, (4-azido)Phe(3)-

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of argipressin, (4-azido)Phe(3)-

There total 4 articles about argipressin, (4-azido)Phe(3)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Cyclo-H-Cys-D-Tyr-Phe(NO2)-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (138783-24-1) → Cyclo-H-Cys-D-Tyr-Phe(N3)-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (97474-07-2)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂, 2N HOAc / Pd/C / 1 h / 6080 Torr

2: 1.) 1N HOAC, β-mercaptoethanol, 2.) 0,1N HCl, 1N NaNO2, NaN3

With hydrogenchloride; sodium azide; hydrogen; acetic acid; 2-hydroxyethanethiol; sodium nitrite; palladium on activated charcoal;

DOI:10.1021/jm00079a020

Reference yield:

Cyclo-H-Cys-Tyr-Phe(NO2)-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (138753-98-7) → Cyclo-H-Cys-Tyr-Phe(N3)-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (97474-07-2)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂, 2N HOAc / Pd/C / 1 h / 6080 Torr

2: 1.) 1N HOAC, β-mercaptoethanol, 2.) 0,1N HCl, 1N NaNO2, NaN3

With hydrogenchloride; sodium azide; hydrogen; acetic acid; 2-hydroxyethanethiol; sodium nitrite; palladium on activated charcoal;

DOI:10.1021/jm00079a020

Reference yield:

C46H66N16O12S2 (101466-19-7) → Cyclo-H-Cys-D-Tyr-Phe(N3)-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (97474-07-2)

Guidance literature:

With hydrogenchloride; sodium azide; acetic acid; 2-hydroxyethanethiol; sodium nitrite; Yield given. Multistep reaction;

DOI:10.1021/jm00079a020

upstream raw materials:

C₄₆H₆₆N₁₆O₁₂S₂

Cyclo-H-Cys-D-Tyr-Phe(NO₂)-Gln-Asn-Cys-Pro-Arg-Gly-NH₂

C₄₆H₆₆N₁₆O₁₂S₂

Cyclo-H-Cys-Tyr-Phe(NO₂)-Gln-Asn-Cys-Pro-Arg-Gly-NH₂

Refernces