2-(6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)acetonitrile

Base Information

Chemical Name:2-(6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)acetonitrile
CAS No.:43052-77-3
Molecular Formula:C13H14N2O2
Molecular Weight:230.266
Hs Code.:
European Community (EC) Number:621-763-1
NSC Number:187770
DSSTox Substance ID:DTXSID10307118
Nikkaji Number:J1.654.768I
Wikidata:Q82054462
Mol file:43052-77-3.mol

Synonyms:43052-77-3;2-(6,7-dimethoxy-3,4-dihydroisoquinolin-1-yl)acetonitrile;(6,7-Dimethoxy-3,4-dihydro-1-isoquinolinyl)acetonitrile;NSC187770;TimTec1_001365;Oprea1_315331;2-(6,7-dimethoxy-3,4-dihydroisoquinolyl)ethanenitrile;DTXSID10307118;HMS1537O01;Cl-1007;AKOS022657370;NSC 187770;NSC-187770;6,7-dimethoxy-3,4-dihydroisoquinolin-1-ylacetonitrile;6,7-Dimethoxy-3,4-dihydroisoquinoline-1-acetonitrile;BRD-K20692460-001-01-6;(6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)acetonitrile

Suppliers and Price of 2-(6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)acetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-(6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)acetonitrile

Chemical Property:

Vapor Pressure:3.18E-06mmHg at 25°C
Boiling Point:387.9°Cat760mmHg
Flash Point:188.4°C
Density:1.16g/cm³
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:230.105527694
Heavy Atom Count:17
Complexity:345

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:COC1=C(C=C2C(=C1)CCN=C2CC#N)OC

Technology Process of 2-(6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)acetonitrile

There total 6 articles about 2-(6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 98841-65-7
2-cyano-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide

: 43052-77-3
(3,4-dihydro-6,7-dimethoxyisoquinolin-1-yl)acetonitrile

Guidance literature:: With phosphorus pentoxide; In toluene; Reflux;
DOI:10.1134/S1070428011050137

Reference yield: 50.0%

: 52244-06-1
2‐(6,7‐dimethoxy‐1,2,3,4‐tetrahydroisoquinolin‐1‐yl)acetonitrile

: 43052-77-3
(3,4-dihydro-6,7-dimethoxyisoquinolin-1-yl)acetonitrile

Guidance literature:: With sulfur; In pyridine; 1.) 12 h, 100 deg C, 2.) 12 h, r.t.;

Reference yield:

: 120-20-7
2-(3,4-dimethoxyphenyl)-ethylamine

: 43052-77-3
(3,4-dihydro-6,7-dimethoxyisoquinolin-1-yl)acetonitrile

Guidance literature:: Multi-step reaction with 2 steps

2: P₂O₅; toluene

With phosphorus pentoxide; toluene;
DOI:10.1039/jr9310000036