N,N-Diethyl-alpha-methyl-4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolineacetamide

Base Information

Chemical Name:N,N-Diethyl-alpha-methyl-4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolineacetamide
CAS No.:83408-97-3
Molecular Formula:C₂₄H₂₉N₃O₅
Molecular Weight:439.511
Hs Code.:2933990090
DSSTox Substance ID:DTXSID101003404
Mol file:83408-97-3.mol

Synonyms:BRN 4598980;83408-97-3;N,N-Diethyl-alpha-methyl-4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolineacetamide;3(4H)-Quinazolineacetamide, N,N-diethyl-alpha-methyl-4-oxo-2-(3,4,5-trimethoxyphenyl)-;DTXSID101003404;LS-139939;N,N-Diethyl-2-[4-oxo-2-(3,4,5-trimethoxyphenyl)quinazolin-3(4H)-yl]propanamide

Suppliers and Price of N,N-Diethyl-alpha-methyl-4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolineacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3(4H)-QUINAZOLINEACETAMIDE, N,N-DIETHYL-ALPHA-METHYL-4-OXO-2-(3,4,5-TR IMETHOXYPHENYL)- 95.00%
5MG
$ 502.06

Total 1 raw suppliers

Chemical Property of N,N-Diethyl-alpha-methyl-4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolineacetamide

Chemical Property:

Vapor Pressure:3.57E-14mmHg at 25°C
Boiling Point:596.1°Cat760mmHg
Flash Point:314.3°C
PSA：82.89000
Density:1.19g/cm³
LogP:3.51870
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:439.21072103
Heavy Atom Count:32
Complexity:681

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

3(4H)-QUINAZOLINEACETAMIDE, N,N-DIETHYL-ALPHA-METHYL-4-OXO-2-(3,4,5-TR IMETHOXYPHENYL)- 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)C(=O)C(C)N1C(=NC2=CC=CC=C2C1=O)C3=CC(=C(C(=C3)OC)OC)OC

Technology Process of N,N-Diethyl-alpha-methyl-4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolineacetamide

There total 4 articles about N,N-Diethyl-alpha-methyl-4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolineacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 40728-74-3
2-(3,4,5-trimethoxyphenyl)-4-H-benzo[d][1,3]oxazin-4-one

: 83408-97-3
N,N-Diethyl-2-[4-oxo-2-(3,4,5-trimethoxy-phenyl)-4H-quinazolin-3-yl]-propionamide

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / pyridine; H₂O / 10 h / Heating

2: SOCl₂ / benzene / 6 h / Heating

3: 69 percent / benzene / 2 h / Heating

With thionyl chloride; In pyridine; water; benzene;

Reference yield:

: 4521-61-3
3,4,5-Trimethoxybenzoyl chloride

: 83408-97-3
N,N-Diethyl-2-[4-oxo-2-(3,4,5-trimethoxy-phenyl)-4H-quinazolin-3-yl]-propionamide

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine / 1) 0-5 deg C 2) 1h, room temperature

2: 75 percent / pyridine; H₂O / 10 h / Heating

3: SOCl₂ / benzene / 6 h / Heating

4: 69 percent / benzene / 2 h / Heating

With pyridine; thionyl chloride; In pyridine; water; benzene;

Reference yield:

: 83408-92-8
2-[4-Oxo-2-(3,4,5-trimethoxy-phenyl)-4H-quinazolin-3-yl]-propionic acid

: 83408-97-3
N,N-Diethyl-2-[4-oxo-2-(3,4,5-trimethoxy-phenyl)-4H-quinazolin-3-yl]-propionamide

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / benzene / 6 h / Heating

2: 69 percent / benzene / 2 h / Heating

With thionyl chloride; In benzene;