Urea, 1-(4,7-dimethoxy-6-(3-piperidinopropoxy)-5-benzofuranyl)-3-methyl-

Base Information

Chemical Name:Urea, 1-(4,7-dimethoxy-6-(3-piperidinopropoxy)-5-benzofuranyl)-3-methyl-
CAS No.:66203-03-0
Molecular Formula:C20H29N3O5
Molecular Weight:391.4614
Hs Code.:
DSSTox Substance ID:DTXSID20216383
Nikkaji Number:J87.691G
Wikidata:Q83092606
ChEMBL ID:CHEMBL295794

Synonyms:BRN 5161713;Urea, 1-(4,7-dimethoxy-6-(3-piperidinopropoxy)-5-benzofuranyl)-3-methyl-;66203-03-0;N-(4,7-Dimethoxy-6-(3-piperidinopropoxy)-5-benzofuranyl)-N'-methylurea;CHEMBL295794;DTXSID20216383;LS-159931;1-[4,7-Dimethoxy-6-(3-piperidinopropoxy)benzofuran-5-yl]-3-methylurea

Suppliers and Price of Urea, 1-(4,7-dimethoxy-6-(3-piperidinopropoxy)-5-benzofuranyl)-3-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Urea, 1-(4,7-dimethoxy-6-(3-piperidinopropoxy)-5-benzofuranyl)-3-methyl-

Chemical Property:

Vapor Pressure:1.93E-11mmHg at 25°C
Boiling Point:533°Cat760mmHg
Flash Point:276.2°C
PSA：88.69000
Density:1.197g/cm³
LogP:3.67140
XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:391.21072103
Heavy Atom Count:28
Complexity:489

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC(=O)NC1=C(C2=C(C(=C1OCCCN3CCCCC3)OC)OC=C2)OC

Technology Process of Urea, 1-(4,7-dimethoxy-6-(3-piperidinopropoxy)-5-benzofuranyl)-3-methyl-

There total 2 articles about Urea, 1-(4,7-dimethoxy-6-(3-piperidinopropoxy)-5-benzofuranyl)-3-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 75883-98-6
4,7-Dimethoxy-6-(3-piperidin-1-yl-propoxy)-benzofuran-5-ylamine

: 624-83-9
methyl isocyanate

: 66203-03-0
1-[4,7-Dimethoxy-6-(3-piperidin-1-yl-propoxy)-benzofuran-5-yl]-3-methyl-urea

Guidance literature:: In toluene; for 5h; Ambient temperature;
DOI:10.1021/jm00134a007

Reference yield:

: 66203-15-4
N-[4,7-Dimethoxy-6-(3-piperidin-1-yl-propoxy)-benzofuran-5-yl]-acetamide; compound with methanesulfonic acid

: 66203-03-0
1-[4,7-Dimethoxy-6-(3-piperidin-1-yl-propoxy)-benzofuran-5-yl]-3-methyl-urea

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / 2 N HCl / 5 h / Heating

2: 59 percent / toluene / 5 h / Ambient temperature

With hydrogenchloride; In toluene;
DOI:10.1021/jm00134a007