(16α,19E)-1-Acetyl-19,20-didehydrocuran-17-ol

Base Information

• Chemical Name: (16α,19E)-1-Acetyl-19,20-didehydrocuran-17-ol
• CAS No.: 2616-16-2
• Molecular Formula: C₂₁H₂₆N₂O₂
• Molecular Weight: 338.45
• Mol file: 2616-16-2.mol

Synonyms:Retuline(7CI,8CI); 3,5-Ethano-3H-pyrrolo[2,3-d]carbazole, curan-17-ol deriv.; NSC325309

Chemical Property of (16α,19E)-1-Acetyl-19,20-didehydrocuran-17-ol

Chemical Property:

• Vapor Pressure: 2.34E-13mmHg at 25°C
• Melting Point: l67-l73°C
• Boiling Point: 559.6°C at 760 mmHg
• Flash Point: 292.2°C
• PSA: 43.78000
• Density: 1.28g/cm³
• LogP: 2.32500

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: This alkaloid has been isolated from Strychnos holstii var. reticulata f. condensata and may be purified by recrystallization from AcOEt or heptane when it yields clusters of colourless needles. It is dextrorotatory with [α]D + 23° (c 0.7, MeOH) and gives an ultraviolet spectrum which exhibits a single absorption maximum at 254.4 mIJ.. It is only sparingly soluble in heptane or Et20, more so in C6H6 and freely soluble in MeOH, EtOH, Me2CO or CHC13. The alkaloid has been synthesized via the lactam produced from strychnine or the WielandGumlich aldehyde.

Technology Process of (16α,19E)-1-Acetyl-19,20-didehydrocuran-17-ol

There total 7 articles about (16α,19E)-1-Acetyl-19,20-didehydrocuran-17-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Isoretulin (2616-16-2,10388-62-2)

Guidance literature:

19;

DOI:10.1016/S0031-9422(00)85234-6

Reference yield:

→ 7-acetyl-12-ethylidene-6-hydroxymethyl-1,2,3a,4,5,6,6a,7-octahydro-3,5-ethano-pyrrolo[2,3-d]carbazole (2616-16-2,10388-62-2)

Guidance literature:

Akuammicinol 4;

DOI:10.1016/S0031-9422(00)97503-4

Reference yield:

→ Retulin (2616-16-2,10388-62-2)

Guidance literature:

O-Acetyl-retulin, Me., wss. NaOH, Raumt.;

upstream raw materials:

strychnidin-10-one