Technology Process of 4,5-Dichloro-1,3,6-trihydroxy-8-methyl-9H-xanthen-9-one
There total 9 articles about 4,5-Dichloro-1,3,6-trihydroxy-8-methyl-9H-xanthen-9-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 13.6 g / potassium carbonate / dimethylformamide / 24 h
2: 5.1 g / trifluoroacetic anhydride / CH2Cl2 / 5 h / Ambient temperature
3: hydrogen, aq. hydrochloric acid / palladized charcoal / ethyl acetate
4: potassium hydroxide / ethanol / 1.5 h / Heating
5: 520 mg / piperidine, water / 66 h / Heating
With
piperidine; hydrogenchloride; potassium hydroxide; water; hydrogen; potassium carbonate; trifluoroacetic anhydride;
palladium on activated charcoal;
In
ethanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: hydrogen, aq. hydrochloric acid / palladized charcoal / ethyl acetate
2: potassium hydroxide / ethanol / 1.5 h / Heating
3: 520 mg / piperidine, water / 66 h / Heating
With
piperidine; hydrogenchloride; potassium hydroxide; water; hydrogen;
palladium on activated charcoal;
In
ethanol; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 10.4 g / potassium carbonate / dimethylformamide / 15 h
2: 9.7 g / potassium hydroxide, water / dimethylsulfoxide / 6 h / Heating
3: 5.1 g / trifluoroacetic anhydride / CH2Cl2 / 5 h / Ambient temperature
4: hydrogen, aq. hydrochloric acid / palladized charcoal / ethyl acetate
5: potassium hydroxide / ethanol / 1.5 h / Heating
6: 520 mg / piperidine, water / 66 h / Heating
With
piperidine; hydrogenchloride; potassium hydroxide; water; hydrogen; potassium carbonate; trifluoroacetic anhydride;
palladium on activated charcoal;
In
ethanol; dichloromethane; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide;