D-Ribofuranose1-dihydrogenphosphate (dicyclohexanamine)

Base Information

• Chemical Name: D-Ribofuranose1-dihydrogenphosphate (dicyclohexanamine)
• CAS No.: 58459-37-3
• Molecular Formula: C5 H11 O8 P
• Molecular Weight: 428.463
• Hs Code.: 29400090
• European Community (EC) Number: 261-263-7
• DSSTox Substance ID: DTXSID70974007
• Mol file: 58459-37-3.mol

Synonyms:D-Ribofuranose1-dihydrogenphosphate (dicyclohexanamine);cyclohexanamine;[(3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl] dihydrogen phosphate;Cyclohexanamine hemi((3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl phosphate);DTXSID70974007;SSHMAENVNUVVFI-VNISEONSSA-N;EINECS 261-263-7;D-Ribofuranose 1-(dihydrogen phosphate), compound with cyclohexylamine (1:2);HY-134529A;CS-0652819;D-Ribose 1-phosphate,biscyclohexylammonium salt;Cyclohexanamine--1-O-phosphonopentofuranose (2/1);D-Ribose 1-phosphate bis(cyclohexylammonium) salt, >=99.0% (TLC)

Chemical Property of D-Ribofuranose1-dihydrogenphosphate (dicyclohexanamine)

Chemical Property:

• Vapor Pressure: 4.71E-16mmHg at 25°C
• Melting Point: 172-175°C dec.
• Boiling Point: 583.7°Cat760mmHg
• Flash Point: 306.8°C
• PSA: 198.53000
• Density: g/cm³
• LogP: 1.49090
• Storage Temp.: −20°C
• Solubility.: Methanol (Slightly), Water (Slightly)
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 3
• Exact Mass: 428.22875314
• Heavy Atom Count: 28
• Complexity: 284

Purity/Quality:

98%min ^*data from raw suppliers

D-Ribose 1-Phosphate, Biscyclohexylammonium Salt ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1CCC(CC1)N.C1CCC(CC1)N.C(C1C(C(C(O1)OP(=O)(O)O)O)O)O
• Isomeric SMILES: C1CCC(CC1)N.C1CCC(CC1)N.C([C@@H]1[C@H]([C@H](C(O1)OP(=O)(O)O)O)O)O
• Uses: D-RIBOSE 1-PHOSPHATE, BISCYCLOHEXYLAMMONIUM SALT is used in the production of cytosine nucleoside compounds Used in the production of cytosine nucleoside compounds.

Technology Process of D-Ribofuranose1-dihydrogenphosphate (dicyclohexanamine)

There total 2 articles about D-Ribofuranose1-dihydrogenphosphate (dicyclohexanamine) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

bis(cyclohexylammonium) phosphate (37832-40-9,36011-98-0) + 7-methylguanosine hydroiodide (81100-62-1) → α-D-ribofuranose-1-O-phosphate bis(cyclohexylammonium) salt (58459-37-3)

Guidance literature:

With purine nucleoside phosphorylase; In water; at 20 ℃; for 5h; Enzymatic reaction;

DOI:10.1002/ejoc.201901454

Reference yield:

G (118-00-3) → α-D-ribofuranose-1-O-phosphate bis(cyclohexylammonium) salt (58459-37-3)

Guidance literature:

Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 24 h / 30 °C

2: purine nucleoside phosphorylase / water / 5 h / 20 °C / Enzymatic reaction

With purine nucleoside phosphorylase; In water; N,N-dimethyl-formamide;

DOI:10.1002/ejoc.201901454

Reference yield: 81.0%

α-D-ribofuranose-1-O-phosphate bis(cyclohexylammonium) salt (58459-37-3) → α-D-ribofuranosyl 1,2-cyclic phosphate monocyclohexylammonium salt

Guidance literature:

With ammonium hydroxide; dicyclohexyl-carbodiimide; In formamide; tert-butyl alcohol; for 2.7h; Heating;

DOI:10.1021/jo00372a008

upstream raw materials:

bis(cyclohexylammonium) phosphate

7-methylguanosine hydroiodide

G

Downstream raw materials:

adenosine

Refernces