2-Methylarginine

Base Information

• Chemical Name: 2-Methylarginine
• CAS No.: 59574-26-4
• Molecular Formula: C₇H₁₆N₄O₂
• Molecular Weight: 188.23
• DSSTox Substance ID: DTXSID80974977
• Nikkaji Number: J175.442D
• Wikidata: Q82959460
• Metabolomics Workbench ID: 98129
• Mol file: 59574-26-4.mol

Synonyms:2-methylarginine;2-methylarginine, (D)-isomer;C(alpha)-methyl-arginine;C(alpha)-methylarginine

Chemical Property of 2-Methylarginine

Chemical Property:

• Vapor Pressure: 1.04E-07mmHg at 25°C
• Boiling Point: 405.4°C at 760 mmHg
• Flash Point: 199°C
• Density: 1.35g/cm³
• XLogP3: -4
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 188.12732577
• Heavy Atom Count: 13
• Complexity: 213

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(CCCN=C(N)N)(C(=O)O)N
• Isomeric SMILES: C[C@](CCCN=C(N)N)(C(=O)O)N

Technology Process of 2-Methylarginine

There total 4 articles about 2-Methylarginine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Methyl-DL-arginin-2-nitroindandionsalz (59574-22-0) → (R)-2-Amino-5-guanidino-2-methyl-pentanoic acid (59574-26-4)

Guidance literature:

With ammonium hydroxide; ion-exchange resin + form>;

DOI:10.7164/antibiotics.29.221

Reference yield:

[3-(4-methyl-2,5-dioxo-imidazolidin-4-yl)-propyl]-guanidine (59545-83-4) → α-Methylarginin (59574-21-9,59574-26-4)

Guidance literature:

With hydrogenchloride;

DOI:10.7164/antibiotics.29.221

Reference yield:

O-methylisourea hemisulfate (29427-58-5,24285-39-0) + 2-Methyl-L-ornithin-hydrochlorid (55301-49-0) → 2-Methyl-L-arginin (59574-26-4)

Guidance literature:

Multistep reaction; (i) CuCO₃, (ii) /BRN= 3722928/, aq. NaOH;

DOI:10.7164/antibiotics.29.221

upstream raw materials:

[3-(4-methyl-2,5-dioxo-imidazolidin-4-yl)-propyl]-guanidine

O-methylisourea hemisulfate

2-Methyl-L-ornithin-hydrochlorid

2-Methyl-DL-arginin-2-nitroindandionsalz