(2alpha,3alpha,5alpha,6xi,11xi,12R)-3-hydroxy-12,13-epoxytrichothecane-4,15-diyl diacetate

Base Information

• Chemical Name: (2alpha,3alpha,5alpha,6xi,11xi,12R)-3-hydroxy-12,13-epoxytrichothecane-4,15-diyl diacetate
• CAS No.: 2270-42-0
• Molecular Formula: C₁₉H₂₈O₇
• Molecular Weight: 368.427
• Mol file: 2270-42-0.mol

Synonyms:Trichothecane-3a,4b,15-triol, 12,13-epoxy-, 4,15-diacetate (8CI);Spiro[2,5-methano-1-benzoxepin-10,2'-oxirane], trichothecane-3,4,15-triolderiv.; 4b,15-Diacetoxy-12,13-epoxytrichothecan-3a-ol; NSC 267032; Scirpane-3a,4b,15-triol, 4,15-diacetate

Chemical Property of (2alpha,3alpha,5alpha,6xi,11xi,12R)-3-hydroxy-12,13-epoxytrichothecane-4,15-diyl diacetate

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 467.788°C at 760 mmHg
• Flash Point: 160.376°C
• Density: 1.288g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2alpha,3alpha,5alpha,6xi,11xi,12R)-3-hydroxy-12,13-epoxytrichothecane-4,15-diyl diacetate

There total 3 articles about (2alpha,3alpha,5alpha,6xi,11xi,12R)-3-hydroxy-12,13-epoxytrichothecane-4,15-diyl diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

T-2 toxin (21259-20-1) → 4,15-Diacetoxy-scirpan-3-ol (2270-42-0,118204-89-0,118243-16-6) + 4β,15-Diacetoxy-3α-hydroxy-8α-<(3-methylbutyryl)oxy>-12,13-epoxytrichothecane

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 5h; Ambient temperature;

DOI:10.1021/jm00123a008

Reference yield:

→ 4β,15-Diacetoxyscirpan-3α-ol (2270-42-0,118204-89-0,118243-16-6)

Guidance literature:

Diacetoxyscirpenol, H2-Pd/C, EtOH;

DOI:10.1002/hlca.19650480434

Reference yield:

→ 4,15-Diacetoxy-scirpan-3-ol (2270-42-0,118204-89-0,118243-16-6)

Guidance literature:

4,15-Diacetoxyscirpen-3-ol, H2-Pt, Eg.;

DOI:10.1039/j39660000116

upstream raw materials:

T-2 toxin