diethyl 2-acetamido-2-[(7-amino-1H-indol-3-yl)methyl]propanedioate

Base Information

• Chemical Name: diethyl 2-acetamido-2-[(7-amino-1H-indol-3-yl)methyl]propanedioate
• CAS No.: 73747-60-1
• Molecular Formula: C₁₈H₂₃N₃O₅
• Molecular Weight: 361.398
• NSC Number: 77008
• DSSTox Substance ID: DTXSID60994638
• Nikkaji Number: J85.371B
• Wikidata: Q82985641
• Mol file: 73747-60-1.mol

Synonyms:73747-60-1;NSC77008;DTXSID60994638;NSC-77008;WLN: T56 BMJ D2VMYVO2&VO2 HZ;N-{2-[(7-Amino-1H-indol-3-yl)methyl]-1,3-diethoxy-1,3-dioxopropan-2-yl}ethanimidic acid

Chemical Property of diethyl 2-acetamido-2-[(7-amino-1H-indol-3-yl)methyl]propanedioate

Chemical Property:

• Vapor Pressure: 9.67E-15mmHg at 25°C
• Boiling Point: 608.3°C at 760 mmHg
• Flash Point: 321.7°C
• PSA: 123.51000
• Density: 1.281g/cm³
• LogP: 2.26580
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 9
• Exact Mass: 361.16377084
• Heavy Atom Count: 26
• Complexity: 521

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C(CC1=CNC2=C1C=CC=C2N)(C(=O)OCC)NC(=O)C

Technology Process of diethyl 2-acetamido-2-[(7-amino-1H-indol-3-yl)methyl]propanedioate

There total 1 articles about diethyl 2-acetamido-2-[(7-amino-1H-indol-3-yl)methyl]propanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ α-Acetamino-α-ethoxycarbonyl-β-(7-amino-3-indolyl)-propionsaeureethylester (73747-60-1)

Guidance literature:

α-Acetamino-α-ethoxycarbonyl-β-(7-nitro-3-indolyl)-propionsaeureethylester (III), Palladium-Kohle, A., Hydrierung;

DOI:10.1139/v64-189