Ravenelin

Base Information

• Chemical Name: Ravenelin
• CAS No.: 479-44-7
• Molecular Formula: C14H10O5
• Molecular Weight: 0
• UNII: O62G6Y2U7J
• DSSTox Substance ID: DTXSID50498458
• Nikkaji Number: J12.536I
• Wikidata: Q27285382
• Mol file: 479-44-7.mol

Synonyms:Ravenelin;O62G6Y2U7J;1,4,8-Trihydroxy-3-methylxanthone;479-44-7;UNII-O62G6Y2U7J;9H-Xanthen-9-one, 1,4,8-trihydroxy-3-methyl-;1,4,8-Trihydroxy-3-methyl-9H-xanthen-9-one;DTXSID50498458;Q27285382

Chemical Property of Ravenelin

Chemical Property:

• PSA: 90.90000
• LogP: 2.37140
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 258.05282342
• Heavy Atom Count: 19
• Complexity: 371

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C2C(=C1O)OC3=CC=CC(=C3C2=O)O)O

Technology Process of Ravenelin

There total 9 articles about Ravenelin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

2,6-dihydroxybenzaldehyde (387-46-2) + 2-Methyl-1,4-benzoquinone (553-97-9) → ravenelin (479-44-7) + 1,4,8-trihydroxy-2-methyl-9H-xanthen-9-one

Guidance literature:

With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium acetate; In 1,2-dichloro-ethane; at 90 ℃; for 16h; regioselective reaction;

DOI:10.1021/acs.orglett.1c00391

Reference yield:

1,4,8-trimethoxy-3-methyl-xanthen-9-one (66951-37-9) → ravenelin (479-44-7)

Guidance literature:

With hydrogen iodide;

Reference yield:

1,4-dihydroxy-8-methoxy-3-methyl-xanthen-9-one (108012-14-2) → ravenelin (479-44-7)

Guidance literature:

With hydrogen iodide; acetic anhydride;

upstream raw materials:

1,4,8-trimethoxy-3-methyl-xanthen-9-one

1,4-dihydroxy-8-methoxy-3-methyl-xanthen-9-one

orcinol

2-hydroxy-6-methoxybenzoic acid