2-(3,4-DIMETHOXYPHENYL)-1H-BENZIMIDAZOLE

Base Information

• Chemical Name: 2-(3,4-DIMETHOXYPHENYL)-1H-BENZIMIDAZOLE
• CAS No.: 2620-85-1
• Molecular Formula: C15H14 N2 O2
• Molecular Weight: 254.288
• Hs Code.: 2933990090
• Mol file: 2620-85-1.mol

Synonyms:Benzimidazole,2-(3,4-dimethoxyphenyl)- (7CI,8CI); NSC 403435

Chemical Property of 2-(3,4-DIMETHOXYPHENYL)-1H-BENZIMIDAZOLE

Chemical Property:

• Vapor Pressure: 2.24E-08mmHg at 25°C
• Boiling Point: 452.4°C at 760 mmHg
• Flash Point: 162.3°C
• PSA: 47.14000
• Density: 1.22g/cm³
• LogP: 3.24710

Purity/Quality:

1H-BENZIMIDAZOLE, 2-(3,4-DIMETHOXYPHENYL)- 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-(3,4-Dimethoxyphenyl)benzimidazole is used in different green activation techniques and its biological activity as antifungal and antimicrobial inhibitor

Technology Process of 2-(3,4-DIMETHOXYPHENYL)-1H-BENZIMIDAZOLE

There total 22 articles about 2-(3,4-DIMETHOXYPHENYL)-1H-BENZIMIDAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3,4-dimethoxy-benzaldehyde (120-14-9) + 1,2-diamino-benzene (95-54-5) → 2-(3,4-dimethoxyphenyl)-1H-benzo[d]imidazole (2620-85-1)

Guidance literature:

With graphite-supported gold nanoparticles; oxygen; In toluene; at 110 ℃; for 2h;

DOI:10.1002/asia.200900261

Reference yield: 92.0%

1,2-diamino-benzene (95-54-5) + (3,4-dimethoxyphenyl)methanol (93-03-8) → 2-(3,4-dimethoxyphenyl)-1H-benzo[d]imidazole (2620-85-1)

Guidance literature:

With C₁₉H₃₅Cl₂CoN₂P; sodium triethylborohydride; In toluene; at 150 ℃; for 36h; Molecular sieve; Schlenk technique;

DOI:10.1021/acscatal.7b02777

Reference yield: 77.0%

3,4-dimethoxybenzylamine (5763-61-1) + 1,2-diamino-benzene (95-54-5) → 2-(3,4-dimethoxyphenyl)-1H-benzo[d]imidazole (2620-85-1)

Guidance literature:

With Al cations incorporated into the Si framework; open air; In neat (no solvent); at 100 ℃; for 15h; Green chemistry;

DOI:10.1039/d1gc02627e

upstream raw materials:

3,4-dimethoxy-benzaldehyde

1,2-diamino-benzene

2-nitro-aniline

C₁₄H₂₀NO₃S⁽¹⁺⁾*I^(1-)

Downstream raw materials:

1-ferrocenylmethyl-2-(3,4-dimethoxyphenyl)-1H-benzimidazole

2-(3',4'-dimethoxyphenyl)-1-methylsulphanylmethyl-1H-benzimidazole

2-(4,5-dimethoxy-2-nitrophenyl)-1H-benzo[d]imidazole