Bicyclo[2.2.2]oct-5-en-2-ol

Base Information

Chemical Name:Bicyclo[2.2.2]oct-5-en-2-ol
CAS No.:6688-07-9
Molecular Formula:C₈H₁₂O
Molecular Weight:124.183
Hs Code.:
NSC Number:167505
DSSTox Substance ID:DTXSID50940907
Nikkaji Number:J99.952K

Synonyms:Bicyclo[2.2.2]oct-5-en-2-ol;55320-40-6;BICYCLO[2.2.2]OCT-2-EN-7-OL;19245-72-8;NSC167505;starbld0026926;SCHEMBL3834374;Bicyclo(2.2.2)oct-5-en-2-ol, (1alpha,2beta,4alpha)-;DTXSID50940907;KEXYAVHJBNJUCG-UHFFFAOYSA-N;Bicyclo[2,2,2]oct-5-en-2-ol;NSC-167505;Bicyclo(2.2.2)oct-5-en-2-ol, (1alpha,2alpha,4alpha)-;Bicyclo[2.2.2]oct-5-en-2-ol-(1.alpha.,2.alpha.,4.alpha.)-;Bicyclo[2.2.2]oct-5-en-2-ol-(1.alpha.,2.beta.,4.alpha.)-

Suppliers and Price of Bicyclo[2.2.2]oct-5-en-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Bicyclo[2.2.2]oct-5-en-2-ol

Chemical Property:

Vapor Pressure:0.0597mmHg at 25°C
Boiling Point:205.4°C at 760 mmHg
Flash Point:73.1°C
Density:1.096g/cm³
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:124.088815002
Heavy Atom Count:9
Complexity:140

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2C=CC1CC2O

Technology Process of Bicyclo[2.2.2]oct-5-en-2-ol

There total 37 articles about Bicyclo[2.2.2]oct-5-en-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 68908-13-4,2220-40-8,16196-15-9,68069-67-0
bicyclo[2.2.2]oct-5-en-2-one

: 6688-07-9,19245-72-8,55320-40-6,68069-65-8,68069-66-9,70981-36-1,74958-54-6,123001-31-0
5-hydroxybicyclo[2.2.2]oct-2-ene

: 6688-07-9,19245-72-8,55320-40-6,68069-65-8,68069-66-9,70981-36-1,74958-54-6,123001-31-0
hydroxy-5 exo bicyclo<2.2.2>octene-2

Guidance literature:: With sodium tetrahydroborate; In isopropyl alcohol;
DOI:10.1021/ja00898a022

Reference yield:

: 68908-13-4,2220-40-8,16196-15-9,68069-67-0
bicyclo[2.2.2]oct-5-en-2-one

: 6688-07-9,19245-72-8,55320-40-6,68069-65-8,68069-66-9,70981-36-1,74958-54-6,123001-31-0
5-hydroxybicyclo[2.2.2]oct-2-ene

: 6688-07-9,19245-72-8,55320-40-6,68069-65-8,68069-66-9,70981-36-1,74958-54-6,123001-31-0
hydroxy-5 exo bicyclo<2.2.2>octene-2

Guidance literature:: With sodium tetrahydroborate; In isopropyl alcohol;
DOI:10.1021/ja00898a022

Reference yield:

: 2-[2'-(phenyldimethylsilyl)-3'-cyclohexenyl]-1-ethanal

: 6688-07-9,19245-72-8,55320-40-6,68069-65-8,68069-66-9,70981-36-1,74958-54-6,123001-31-0
5-hydroxybicyclo[2.2.2]oct-2-ene

Guidance literature:: 2-[2'-(phenyldimethylsilyl)-3'-cyclohexenyl]-1-ethanal; With trifluorormethanesulfonic acid; In dichloromethane; at -78 ℃; for 0.0166667h;

With methanol; sodium hydroxide; In dichloromethane; at -78 - 20 ℃; for 2h; optical yield given as %de; diastereoselective reaction;
DOI:10.1016/j.tet.2012.05.084