3-Methoxy-1H-pyrazolo[4,3-e][1,2,4]triazine

Base Information

• Chemical Name: 3-Methoxy-1H-pyrazolo[4,3-e][1,2,4]triazine
• CAS No.: 37526-53-7
• Molecular Formula: C5H5N5O
• Molecular Weight: 0
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID10418713
• Nikkaji Number: J882.995K
• ChEMBL ID: CHEMBL1369388
• Mol file: 37526-53-7.mol

Synonyms:3-Methoxy-1H-pyrazolo[4,3-e][1,2,4]triazine;Fluviol A;BAS 00463315;37526-53-7;ChemDiv2_000626;MLS000076555;CHEMBL1369388;SCHEMBL16431132;SCHEMBL16431137;DTXSID10418713;JZRGCUJFJFYJCX-UHFFFAOYSA-N;HMS1370M10;HMS2166J14;HMS3323H20;STK177239;AKOS000715051;SMR000008962;2-Methoxy-1H-pirazolo[4,3-E][1,2,4]triazine;1H-Pyrazolo[4,3-E]1,2,4-triazine, 3-methoxy-;1H-Pyrazolo[4,3-E][1,2,4]-triazine, 3-methoxy-;Methyl 1H-pyrazolo[4,3-E][1,2,4]triazin-3-yl ether #

Chemical Property of 3-Methoxy-1H-pyrazolo[4,3-e][1,2,4]triazine

Chemical Property:

• Vapor Pressure: 0.000109mmHg at 25°C
• Boiling Point: 347.3°C at 760 mmHg
• Flash Point: 126.9°C
• PSA: 76.58000
• Density: 1.53g/cm³
• LogP: -0.24350
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 151.04940980
• Heavy Atom Count: 11
• Complexity: 143

Purity/Quality:

99% ^*data from raw suppliers

3-METHOXY-1H-PYRAZOLO[4,3-E][1,2,4]TRIAZINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=NNC2=C1N=CN=N2

Technology Process of 3-Methoxy-1H-pyrazolo[4,3-e][1,2,4]triazine

There total 2 articles about 3-Methoxy-1H-pyrazolo[4,3-e][1,2,4]triazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

1,2-dihydro-3H-pyrazolo[4,3-e][1,2,4]triazin-3-one hydrochloride + diazomethyl-trimethyl-silane (18107-18-1) → fluviol A (37526-53-7) + nostocine A

Guidance literature:

In methanol; acetonitrile; at 20 ℃; for 1.5h;

DOI:10.1021/ja060937l

Reference yield:

→ fluviol A (37526-53-7)

Guidance literature:

1, Stehenlassen der Loesung;

DOI:10.1002/cber.19721050619

upstream raw materials:

diazomethyl-trimethyl-silane