Prostaglandin D2 1,15-lactone

Base Information

Chemical Name:Prostaglandin D2 1,15-lactone
CAS No.:62410-98-4
Molecular Formula:C20H30O4
Molecular Weight:334.45
Hs Code.:

Synonyms:Prostaglandin D2 1,15-lactone;PGD2 1,15-lactone;BRN 5600045;Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, lambda-lactone, (5Z,9-alpha,13E,15S)-;62410-98-4;LS-125824

Suppliers and Price of Prostaglandin D2 1,15-lactone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Prostaglandin D2 1,15-lactone

Chemical Property:

Vapor Pressure:4.53E-13mmHg at 25°C
Boiling Point:521.8°C at 760 mmHg
PKA:13.74±0.40(Predicted)
Flash Point:180.9°C
PSA：63.60000
Density:1.046g/cm³
LogP:3.73100
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:334.21440943
Heavy Atom Count:24
Complexity:480

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCC1C=CC2C(CC=CCCCC(=O)O1)C(CC2=O)O
Isomeric SMILES:CCCCC[C@H]1/C=C/[C@@H]2[C@@H](C/C=C\CCCC(=O)O1)[C@H](CC2=O)O

Technology Process of Prostaglandin D2 1,15-lactone

There total 5 articles about Prostaglandin D2 1,15-lactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 62411-02-3
(4E,12Z)-(1S,3aR,6S,14aR)-6-Pentyl-1-(tetrahydro-pyran-2-yloxy)-1,3a,6,9,10,11,14,14a-octahydro-2H-7-oxa-cyclopentacyclotridecene-3,8-dione

: 62410-98-4
PGD₂ 1,15-lactone

Guidance literature:: With acetic acid; In tetrahydrofuran; water; at 40 ℃; for 3h;
DOI:10.1021/jm00360a003

Reference yield:

: 55314-49-3
PGF_2α 1,15-lactone

: 62410-98-4
PGD₂ 1,15-lactone

Guidance literature:: Multi-step reaction with 5 steps

1: 82 percent / imidazole / dimethylformamide / 1 h / 0 °C

2: 92 percent / pyridine hydrochloride / CH₂Cl₂ / 18 h / 25 °C

3: tetrabutylammonium fluoride / tetrahydrofuran / 0.5 h / 25 °C

4: H₂CrO₄, H₂SO₄ / acetone / 1.25 h / -30 - -20 °C

5: 243 mg / AcOH / H₂O; tetrahydrofuran / 3 h / 40 °C

With 1H-imidazole; sulfuric acid; tetrabutyl ammonium fluoride; pyridine hydrochloride; chromic acid; acetic acid; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; acetone;
DOI:10.1021/jm00360a003

Reference yield:

: 62411-01-2
(4E,12Z)-(1S,3R,3aR,6S,14aR)-3-Hydroxy-6-pentyl-1-(tetrahydro-pyran-2-yloxy)-1,2,3,3a,6,9,10,11,14,14a-decahydro-7-oxa-cyclopentacyclotridecen-8-one

: 62410-98-4
PGD₂ 1,15-lactone

Guidance literature:: Multi-step reaction with 2 steps

1: H₂CrO₄, H₂SO₄ / acetone / 1.25 h / -30 - -20 °C

2: 243 mg / AcOH / H₂O; tetrahydrofuran / 3 h / 40 °C

With sulfuric acid; chromic acid; acetic acid; In tetrahydrofuran; water; acetone;
DOI:10.1021/jm00360a003