Burseran

Base Information

Chemical Name:Burseran
CAS No.:23284-23-3
Molecular Formula:C22H26 O6
Molecular Weight:386.4382
Hs Code.:
Nikkaji Number:J344.389B
Wikidata:Q27105996
Metabolomics Workbench ID:70804
ChEMBL ID:CHEMBL3582087
Mol file:23284-23-3.mol

Synonyms:burseran

Suppliers and Price of Burseran

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Burseran

Chemical Property:

Vapor Pressure:6.54E-10mmHg at 25°C
Boiling Point:507.3°C at 760 mmHg
Flash Point:205°C
Density:1.209g/cm³
XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:386.17293854
Heavy Atom Count:28
Complexity:474

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=C1OC)OC)CC2COCC2CC3=CC4=C(C=C3)OCO4
Isomeric SMILES:COC1=CC(=CC(=C1OC)OC)C[C@@H]2COC[C@H]2CC3=CC4=C(C=C3)OCO4

Technology Process of Burseran

There total 17 articles about Burseran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 72627-53-3
(+)-dihydroclusin

: 23284-23-3
(+)-trans-burseran

Guidance literature:: With hydrogenchloride; In methanol; for 48h; Heating;
DOI:10.1055/s-2002-20967

Reference yield: 71.0%

: (3S,4S)-4-<3,4-(Methylenedioxy)benzyl>-3-<(3,4,5-trimethoxyphenyl)(phenylthio)methyl>tetrahydrofuran

: 23284-23-3
(+)-trans-burseran

Guidance literature:: W-2 Ra-Ni; In ethanol; for 20h; Heating;
DOI:10.1021/jo00060a037

Reference yield:

: 61946-94-9
N-hydroxy-benzo[1,3]dioxole-5-carboximidoyl chloride

: 23284-23-3
(+)-trans-burseran

Guidance literature:: Multi-step reaction with 6 steps

1: 78 percent / NEt₃ / diethyl ether / 15 h / Ambient temperature

2: 91 percent / H₂, boric acid / W-2 Ra-Ni / methanol; H₂O

3: 1) H₂, conc.H₂SO₄ / 1) 10percent Pd/C / 1) EtOH, r,t., overnight, 2) Lipase PS, 13 h

4: 1) MeLi / 1) THF, -78 deg C, 30 min, 2) THF, -78 deg C to r.t., then 3 h

5: 1) n-BuLi / 1) THF, 0 deg C, 30 min, 2) THF, a) 0 deg C, 1-2 h, b) r.t., 17 h

6: 71 percent / W-2 Ra-Ni / ethanol / 20 h / Heating

With n-butyllithium; sulfuric acid; methyllithium; hydrogen; boric acid; triethylamine; palladium on activated charcoal; W-2 Ra-Ni; In methanol; diethyl ether; ethanol; water;
DOI:10.1021/jo00060a037