2-(2-Methylphenoxy)acetohydrazide

Base Information

• Chemical Name: 2-(2-Methylphenoxy)acetohydrazide
• CAS No.: 36304-37-7
• Molecular Formula: C9H12 N2 O2
• Molecular Weight: 180.206
• Hs Code.: 2928000090
• DSSTox Substance ID: DTXSID30351138
• Nikkaji Number: J656.116K
• Wikidata: Q82127310
• Mol file: 36304-37-7.mol

Synonyms:2-(2-methylphenoxy)acetohydrazide;36304-37-7;o-tolyloxy-acetic acid hydrazide;2-(o-Tolyloxy)acetohydrazide;O-TOLYLOXY-ACETICACIDHYDRAZIDE;Oprea1_604610;Oprea1_694216;SCHEMBL11869994;DTXSID30351138;BBL008414;MFCD00553727;STK077797;AKOS000116125;SB86003;VS-01905;BB 0243176;CS-0204394;EN300-03715;SR-01000414678;SR-01000414678-1;Z56869405

Chemical Property of 2-(2-Methylphenoxy)acetohydrazide

Chemical Property:

• Vapor Pressure: 2.26E-06mmHg at 25°C
• Melting Point: 118-119 °C(Solv: ethanol (64-17-5))
• Boiling Point: 392.6°Cat760mmHg
• PKA: 12.23±0.35(Predicted)
• Flash Point: 191.2°C
• PSA: 64.35000
• Density: 1.156g/cm³
• LogP: 1.45490
• XLogP3: 1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 180.089877630
• Heavy Atom Count: 13
• Complexity: 173

Purity/Quality:

98%min ^*data from raw suppliers

2-(2-Methylphenoxy)acetohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=CC=C1OCC(=O)NN

Technology Process of 2-(2-Methylphenoxy)acetohydrazide

There total 10 articles about 2-(2-Methylphenoxy)acetohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methyl 2-methylphenoxy acetate (2989-17-5) → o-tolyloxyacetic acid hydrazide (36304-37-7)

Guidance literature:

With hydrazine hydrate; In methanol; for 0.0166667h; microwave irradiation;

DOI:10.1081/SCC-120027275

Reference yield: 86.0%

ethyl (2-methylphenoxy)acetate (93917-68-1) → o-tolyloxyacetic acid hydrazide (36304-37-7)

Guidance literature:

With hydrazine hydrate; In ethanol; at 20 ℃;

DOI:10.1016/j.molstruc.2021.132173

Reference yield:

o-methylphenoxyacetic acid (1878-49-5) → o-tolyloxyacetic acid hydrazide (36304-37-7)

Guidance literature:

With hydrazine hydrate; sulfuric acid; In methanol; for 25h; Heating;

DOI:10.1211/0022357011775307

upstream raw materials:

methyl 2-methylphenoxy acetate

ethyl (2-methylphenoxy)acetate

o-methylphenoxyacetic acid

ortho-cresol

Downstream raw materials:

4-chloro-N-(N'-o-tolyloxyacetyl-hydrazinocarbothioyl)-benzamide

N-o-tolyloxyacetyl-hydrazinecarbodithioic acid