5-O-Desosaminylerythronolide A oxime

Base Information

• Chemical Name: 5-O-Desosaminylerythronolide A oxime
• CAS No.: 53066-45-8
• Molecular Formula: C₃₁H₅₆N₂O₁₁
• Molecular Weight: 632.792
• Mol file: 53066-45-8.mol

Synonyms:Oxacyclotetradecane,erythromycin deriv.; 3-Acetyl-5-O-desosaminylerythronolide A oxime

Chemical Property of 5-O-Desosaminylerythronolide A oxime

Chemical Property:

• Vapor Pressure: 3.85E-26mmHg at 25°C
• Boiling Point: 752.6°C at 760 mmHg
• PKA: 11.95±0.70(Predicted)
• Flash Point: 408.9°C
• PSA: 187.81000
• Density: 1.27g/cm³
• LogP: 1.69230
• Solubility.: Dichloromethane, Chloroform, Methanol

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 5-O-Desosaminylerythronolide A Oxime is an intermediate in synthesizing Erythrolosamine (E649910), a derivative of Erythromycin A Oxime (E650010), which displays no antibacterial activity. It is a potent precursor of ketolide antibiotics.

Technology Process of 5-O-Desosaminylerythronolide A oxime

There total 1 articles about 5-O-Desosaminylerythronolide A oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-Acetyl-5-O-desosaminyl-erythronolid A-oxim (53066-45-8)

Guidance literature:

Acetoxim 4, Acetanhydrid;

DOI:10.1021/jm00255a009