8-Hydroxy-7-nitroso-5-quinolinesulfonic acid

Base Information

• Chemical Name: 8-Hydroxy-7-nitroso-5-quinolinesulfonic acid
• CAS No.: 5263-74-1
• Molecular Formula: C9H6N2O5S
• Molecular Weight: 254.22
• Hs Code.: 2933499090
• Mol file: 5263-74-1.mol

Synonyms:8-Hydroxy-7-nitroso-5-quinolinesulfonic acid;

Chemical Property of 8-Hydroxy-7-nitroso-5-quinolinesulfonic acid

Chemical Property:

• PSA: 125.30000
• Density: 1.78g/cm³
• LogP: 2.66580

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 8-Hydroxy-7-nitroso-5-quinolinesulfonic acid

There total 2 articles about 8-Hydroxy-7-nitroso-5-quinolinesulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

8-quinolinol-5-sulfonic acid (84-88-8) → 7-Nitroso-8-hydroxyquinoline-5-sulphonic acid (5263-74-1)

Guidance literature:

With sulfuric acid; sodium nitrite; In sodium hydroxide; 1.) 10 deg C, 2.) 0 deg C, 2.5 h;

Reference yield:

→ 7-Nitroso-8-hydroxyquinoline-5-sulphonic acid (5263-74-1)

Guidance literature:

Iodhydroxychinolinsulfonsaeure (1), NaNO2;

DOI:10.1002/ardp.19763091212

Reference yield:

7-Nitroso-8-hydroxyquinoline-5-sulphonic acid (5263-74-1) → 2-(4-Methoxy-phenyl)-oxazolo[4,5-h]quinoline

Guidance literature:

Multi-step reaction with 3 steps

1: 80 percent / SnCl₂, cc. HCl / ethanol / 6 h / Heating

2: 54 percent / cc. HCl / H₂O / 6 h / 170 °C

3: 71 percent / piperidine / ethanol / 8 h / Heating

With piperidine; hydrogenchloride; tin(ll) chloride; In ethanol; water;

upstream raw materials:

8-quinolinol-5-sulfonic acid

Downstream raw materials:

7-Amino-8-hydroxy-chinolin-5-sulfonsaeure

8-hydroxy-7-nitro-quinoline-5-sulfonic acid

Refernces

• 1、 Yanni,Hammam,Khalil,Khalaf,Abdel-Hafez. "Synthesis of some new oxazoloquinolines and stilbyloxazoloquinolines". . p. 218 - 220. Retrieved 2007/10/02.