2-(1,2,3,4-Tetrahydro-6-methoxy-2-phenyl-1-isoquinolinyl)benzenamine

Base Information

Chemical Name:2-(1,2,3,4-Tetrahydro-6-methoxy-2-phenyl-1-isoquinolinyl)benzenamine
CAS No.:96719-50-5
Molecular Formula:C22H22N2O
Molecular Weight:330.4229
Hs Code.:
DSSTox Substance ID:DTXSID40914374

Synonyms:2-(1,2,3,4-Tetrahydro-6-methoxy-2-phenyl-1-isoquinolinyl)benzenamine;Benzenamine, 2-(1,2,3,4-tetrahydro-6-methoxy-2-phenyl-1-isoquinolinyl)-;96719-50-5;DTXSID40914374;LS-28433;2-(6-Methoxy-2-phenyl-1,2,3,4-tetrahydroisoquinolin-1-yl)aniline

Suppliers and Price of 2-(1,2,3,4-Tetrahydro-6-methoxy-2-phenyl-1-isoquinolinyl)benzenamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(1,2,3,4-Tetrahydro-6-methoxy-2-phenyl-1-isoquinolinyl)benzenamine

Chemical Property:

Vapor Pressure:1.69E-10mmHg at 25°C
Boiling Point:509.5°C at 760 mmHg
Flash Point:261.9°C
Density:1.171g/cm³
XLogP3:4.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:330.173213330
Heavy Atom Count:25
Complexity:422

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C(N(CC2)C3=CC=CC=C3)C4=CC=CC=C4N

Technology Process of 2-(1,2,3,4-Tetrahydro-6-methoxy-2-phenyl-1-isoquinolinyl)benzenamine

There total 7 articles about 2-(1,2,3,4-Tetrahydro-6-methoxy-2-phenyl-1-isoquinolinyl)benzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 96719-49-2
6-Methoxy-1-(2-nitro-phenyl)-2-phenyl-1,2,3,4-tetrahydro-isoquinoline

: 96719-50-5
1-(2-aminophenyl)-6-methoxy-2-phenyl-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: With hydrogen; platinum(IV) oxide; In 1,4-dioxane; methanol; at 40 ℃; for 18h;

Reference yield:

: 1798-09-0
m-methoxyphenylacetic acid

: 96719-50-5
1-(2-aminophenyl)-6-methoxy-2-phenyl-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: Multi-step reaction with 7 steps

1: SOCl₂ / benzene / 1 h / Heating

2: diethyl ether / Ambient temperature

3: 74 percent / LAH / dioxane; diethyl ether

4: 1.) SOCl₂ / 1.) benzene, reflux, 2.) ether, r.t.

5: 1.) POCl₃, 2.) KI / 1.) reflux, 2.) H₂O

6: NaBH₄ / methanol

7: 0.7 g / H₂ / PtO₂ / dioxane; methanol / 18 h / 40 °C

With sodium tetrahydroborate; lithium aluminium tetrahydride; thionyl chloride; hydrogen; potassium iodide; trichlorophosphate; platinum(IV) oxide; In 1,4-dioxane; methanol; diethyl ether; benzene;

Reference yield:

: 51009-27-9
[2-(3-Methoxy-phenyl)-ethyl]-phenyl-amine

: 96719-50-5
1-(2-aminophenyl)-6-methoxy-2-phenyl-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) SOCl₂ / 1.) benzene, reflux, 2.) ether, r.t.

2: 1.) POCl₃, 2.) KI / 1.) reflux, 2.) H₂O

3: NaBH₄ / methanol

4: 0.7 g / H₂ / PtO₂ / dioxane; methanol / 18 h / 40 °C

With sodium tetrahydroborate; thionyl chloride; hydrogen; potassium iodide; trichlorophosphate; platinum(IV) oxide; In 1,4-dioxane; methanol;