RL 218

Base Information

Chemical Name:RL 218
CAS No.:153901-56-5
Molecular Formula:C22H23 Cl N6
Molecular Weight:406.91
Hs Code.:
Mol file:153901-56-5.mol

Synonyms:RL 218

Suppliers and Price of RL 218

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of RL 218

Chemical Property:

Vapor Pressure:3.84E-13mmHg at 25°C
Boiling Point:573.1°C at 760 mmHg
Flash Point:300.4°C
PSA：41.60000
Density:1.33g/cm³
LogP:3.95190

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of RL 218

There total 5 articles about RL 218 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 109-01-3
1-methyl-piperazine

: 153901-45-2
8-Chloro-1-methyl-5-methylsulfanyl-6-phenyl-6H-2,3,6,10b-tetraaza-benzo[e]azulene

: 153901-56-5
RL 218

Guidance literature:: With diphenyl ether-biphenyl eutectic; toluene-4-sulfonic acid; at 200 ℃; for 24h;
DOI:10.1016/0223-5234(93)90088-V

Reference yield:

: 54748-06-0
8-chloro-1-methyl-6-phenyl-4H-<1,2,4>triazolo<4,3-a><1,5>benzodiazepin-5(6H)-one

: 153901-56-5
RL 218

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / Lawesson's reagent / various solvent(s) / 0.5 h / 150 °C

2: 80 percent / benzyltriethylammonium chloride (TEBA), 48percent aq. KOH / chlorobenzene / Ambient temperature

3: 52 percent / p-toluenesulphonic acid, Dowtherm A / 24 h / 200 °C

With Lawessons reagent; potassium hydroxide; diphenyl ether-biphenyl eutectic; N-benzyl-N,N,N-triethylammonium chloride; toluene-4-sulfonic acid; In chlorobenzene;
DOI:10.1016/0223-5234(93)90088-V

Reference yield:

: 153901-41-8
8-chloro-1-methyl-6-phenyl-4H-<1,2,4>triazolo<4,3-a><1,5>benzodiazepine-5(6H)-thione

: 153901-56-5
RL 218

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / benzyltriethylammonium chloride (TEBA), 48percent aq. KOH / chlorobenzene / Ambient temperature

2: 52 percent / p-toluenesulphonic acid, Dowtherm A / 24 h / 200 °C

With potassium hydroxide; diphenyl ether-biphenyl eutectic; N-benzyl-N,N,N-triethylammonium chloride; toluene-4-sulfonic acid; In chlorobenzene;
DOI:10.1016/0223-5234(93)90088-V