cyclohexylidenemethyl trifluoromethanesulfonate

Base Information

• Chemical Name: cyclohexylidenemethyl trifluoromethanesulfonate
• CAS No.: 53282-32-9
• Molecular Formula: C8H11F3O3S
• Molecular Weight: 244.235
• Mol file: 53282-32-9.mol

Synonyms:

Chemical Property of cyclohexylidenemethyl trifluoromethanesulfonate

Chemical Property:

• Vapor Pressure: 0.0137mmHg at 25°C
• Boiling Point: 267.1°C at 760 mmHg
• Flash Point: 115.3°C
• Density: 1.458g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of cyclohexylidenemethyl trifluoromethanesulfonate

There total 3 articles about cyclohexylidenemethyl trifluoromethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

trifluoromethylsulfonic anhydride (358-23-6) + cyclohexanecarbaldehyde (2043-61-0) → cyclohexylidenemethyl trifluoromethanesulfonate (53282-32-9)

Guidance literature:

With 2,6-di-tert-butyl-4-methylpyridine; In dichloromethane; for 1h; Heating;

DOI:10.1055/s-1980-28991

Reference yield:

trifluoromethylsulfonic anhydride (358-23-6) + (trimethylsiloxymethylidene)cyclohexane (53282-55-6) → cyclohexylidenemethyl trifluoromethanesulfonate (53282-32-9)

Guidance literature:

With triphenylmethane; methyllithium; In 1,2-dimethoxyethane;

DOI:10.1021/ja00821a034

Reference yield:

cyclohexanecarbaldehyde (2043-61-0) → cyclohexylidenemethyl trifluoromethanesulfonate (53282-32-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / NEt₃ / dimethylformamide / Heating

2: 1) MeLi / 1) 1,2-dimethoxyethane, -60 deg C to 10 deg C, 2) -75 deg C to r.t., overnight

With methyllithium; triethylamine; In N,N-dimethyl-formamide;

upstream raw materials:

trifluoromethylsulfonic anhydride

(trimethylsiloxymethylidene)cyclohexane

cyclohexanecarbaldehyde

Downstream raw materials:

cyclohexylideneacetic acid