2-(2-Aminoethyl)pyridine hydrochloride

Base Information

• Chemical Name: 2-(2-Aminoethyl)pyridine hydrochloride
• CAS No.: 3343-39-3
• Molecular Formula: C₇H₁₀N₂*2ClH
• Molecular Weight: 195.092
• DSSTox Substance ID: DTXSID80179061
• Mol file: 3343-39-3.mol

Synonyms:2-(2-Aminoethyl)pyridine hydrochloride;Pyridine, 2-(2-aminoethyl)-, hydrochloride;24319-18-4;beta-(2-Pyridyl)ethylamine hydrochloride;3668-52-8;2-Pyridylethylamine (hydrochloride);2-(Pyridin-2-yl)ethanamine hydrochloride;SCHEMBL3723683;2-pyridylethylamine hydrochloride;DTXSID80179061;2-pyridineethaneamine hydrochloride;2-Pyridineethanamine, hydrochloride;2-(Pyridin-2-yl)ethanaminehydrochloride;LS-130231;2-(pyridin-2-yl)ethan-1-amine hydrochloride;EN300-7644378

Chemical Property of 2-(2-Aminoethyl)pyridine hydrochloride

Chemical Property:

• Vapor Pressure: 2.88E-05mmHg at 25°C
• Boiling Point: 207.9°Cat760mmHg
• Flash Point: 100.6°C
• PSA: 38.91000
• Density: 1.025g/cm³
• LogP: 2.88710
• Storage Temp.: Desiccate at RT
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 158.0610761
• Heavy Atom Count: 10
• Complexity: 73.3

Purity/Quality:

99% ^*data from raw suppliers

2-Pyridylethylamine dihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=NC(=C1)CCN.Cl
• Uses: 2-Pyridylethylamine dihydrochloride is a histamine H1 receptor agonist that produces vasoconstriction.

Technology Process of 2-(2-Aminoethyl)pyridine hydrochloride

There total 1 articles about 2-(2-Aminoethyl)pyridine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-1-[2]pyridyl-ethanone (75140-33-9) → 2-Pyridylethylamine dihydrochloride (3343-39-3,3668-52-8,24319-18-4)

Guidance literature:

Hydrogenation;

DOI:10.1021/ja01225a017

Reference yield: 73.5%

(R)-1-(3-((3'-(3-bromopropoxy)-2,2'-dimethyl-[1,1'-biphenyl]-3-yl)oxy)propyl)pyrrolidin-3-ol + 2-Pyridylethylamine dihydrochloride (3343-39-3,3668-52-8,24319-18-4) → (R)-1-(3-((2,2'-dimethyl-3'-(3-((2-(pyridin-2-yl)ethyl)amino)propoxy)-[1,1'-biphenyl]-3-yl)oxy)propyl)pyrrolidin-3-ol

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In methanol; at 60 ℃; for 16h; Inert atmosphere;

upstream raw materials:

2-amino-1-[2]pyridyl-ethanone