Spinosad

Base Information

• Chemical Name: Spinosad
• CAS No.: 168316-95-8
• Molecular Formula: C41H65NO10
• Molecular Weight: 731.96
• Mol file: 168316-95-8.mol

Synonyms:Conserve;Entrust;GF 120;GF 120 Fruit Fly Bait;GF 120 NF Naturalyte;GF 120 NaturalyteFruit Fly Bait;Gardens Alive Bulls-Eye;LY 232105;Laser (insecticide);Naturalyte;PP 105;SpinTor;Spinoace;Spinosad NT;Spinosyn A-spinosyn Dmixt.;Success;Success Naturalyte;Tracer;Tracer Naturalyte;XDE 105;

Chemical Property of Spinosad

Chemical Property:

• Appearance/Colour: almost white powder
• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 110℃
• Refractive Index: 1.54
• Boiling Point: 801.515°C at 760 mmHg
• Flash Point: 438.541°C
• PSA: 101.99000
• Density: 1.167g/cm³
• LogP: 6.45490
• Storage Temp.: 0-6°C

Purity/Quality:

99%min ^*data from raw suppliers

Spinosad ^*data from reagent suppliers

Safty Information:

• Pictogram(s): N
• Hazard Codes: N
• Statements: 50/53
• Safety Statements: 61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• General Description: Spinosad is a broad-spectrum, environmentally friendly insecticide derived from fermentation, known for its low toxicity to animals and humans. It is effective against various pests, including *Plutella xylostella* larvae, and serves as a key reference compound in insecticide development. Structural modifications, such as sugar component replacements, can yield analogues with varying insecticidal potency, though few match spinosad's efficacy. Spinosad's activity is influenced by the electrical properties of substituents, underscoring its potential as a model for designing safer and more effective insecticides.

Refernces

Semi-synthesis and insecticidal activity of spinetoram J and its D-forosamine replacement analogues

10.3762/bjoc.14.207

The study focuses on the semi-synthesis and insecticidal activity of spinetoram J and its D-forosamine replacement analogues. Spinetoram, derived from fermentation, is a broad-spectrum insecticide that is environmentally friendly and non-toxic to animals and humans. The researchers improved the semi-synthesis process of spinetoram J by using 3-O-ethyl-2,4-di-O-methylrhamnose as both a reaction substrate and a protecting group, which simplified the synthesis steps and reduced costs. They also synthesized a range of D-forosamine replacement analogues and evaluated their insecticidal activities against Plutella xylostella larvae. Although the analogues did not match the potency of spinetoram, some showed only 20–40 times lower activity, with one analogue being nearly as active as spinosad. The findings suggest the potential for developing new insecticides by modifying sugar components in natural products and highlight the importance of the electrical properties of substituents in insecticidal activity.