5,10-Dihydroindeno[1,2-b]indole

Base Information

• Chemical Name: 5,10-Dihydroindeno[1,2-b]indole
• CAS No.: 3254-91-9
• Molecular Formula: C15H11 N
• Molecular Weight: 205.25
• Hs Code.: 2933990090
• NSC Number: 135344
• DSSTox Substance ID: DTXSID50954281
• Nikkaji Number: J412.230E
• Wikidata: Q82933395
• ChEMBL ID: CHEMBL596060
• Mol file: 3254-91-9.mol

Synonyms:5,10-DHII;5,10-dihydroindeno(1,2-b)indole;indenoindole

Chemical Property of 5,10-Dihydroindeno[1,2-b]indole

Chemical Property:

• Vapor Pressure: 1.3E-06mmHg at 25°C
• Boiling Point: 411.8°Cat760mmHg
• Flash Point: 186.3°C
• PSA: 15.79000
• Density: 1.276g/cm³
• LogP: 3.73910
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 205.089149355
• Heavy Atom Count: 16
• Complexity: 275

Purity/Quality:

99% ^*data from raw suppliers

5,10-dihydro-Indeno[1,2-b]indole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C2=CC=CC=C2C3=C1C4=CC=CC=C4N3

Technology Process of 5,10-Dihydroindeno[1,2-b]indole

There total 2 articles about 5,10-Dihydroindeno[1,2-b]indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 1.3%

2-hydroxyindan-1-one (1579-16-4) + aniline (62-53-3) → 5,6-Dihydroindeno<2,1-b>indole (7156-31-2) + 5,10-dihydroindeno[1,2-b]indole (3254-91-9) + 5,7-dihydro-6-phenyldiindeno<2,1-b,d>pyrrole + (+/-)-5β(α),6a(α),11b(α),11c(α)-tetrahydro-6-phenyldiindan-5,7-diono<2,1-b,d>pyrrole

Guidance literature:

With aniline hydrochloride; at 120 - 130 ℃; for 2h; Further byproducts given;

DOI:10.1016/S0040-4020(01)81911-6

Reference yield: 1.0%

2-hydroxyindan-1-one (1579-16-4) + aniline (62-53-3) → 5,6-Dihydroindeno<2,1-b>indole (7156-31-2) + 5,10-dihydroindeno[1,2-b]indole (3254-91-9) + 5,7-dihydro-6-phenyldiindeno<2,1-b,d>pyrrole + 11,12-dihydro-5-phenyldiindeno<1,2-b,d>pyrrole (115679-37-3)

Guidance literature:

With aniline hydrochloride; at 120 - 130 ℃; for 2h; Further byproducts given;

DOI:10.1016/S0040-4020(01)81911-6

Reference yield: 98.0%

5,10-dihydroindeno[1,2-b]indole (3254-91-9) → cis-4b,5,9b,10-tetrahydroindeno<1,2-b>indole (133571-34-3)

Guidance literature:

With sodium cyanoborohydride; In acetic acid; for 3h; below 18 deg C;

DOI:10.1016/S0040-4020(01)87108-8

upstream raw materials:

2-hydroxyindan-1-one

aniline

Downstream raw materials:

5-benzoyl-5,10-dihydro-indeno[1,2-b]indole

cis-4b,5,9b,10-tetrahydroindeno<1,2-b>indole

5,10-dihydroindeno<1,2-b>indol-10-one

(Z)-5,5',10,10'-tetrahydro-10,10'-biindeno<1,2-b>indolylidenes