1-Phenethyl-4-piperidone

Base Information Edit

Chemical Name:1-Phenethyl-4-piperidone
CAS No.:39742-60-4
Molecular Formula:C13H17NO
Molecular Weight:203.284
Hs Code.:29333999
European Community (EC) Number:254-613-5
NSC Number:74494
UNII:CIS0S4O95K
DSSTox Substance ID:DTXSID30192826
Nikkaji Number:J83.625G
Wikipedia:N-Phenethyl-4-piperidinone
Wikidata:Q6951396
Mol file:39742-60-4.mol

Synonyms:1-Phenethyl-4-piperidone;39742-60-4;1-phenethylpiperidin-4-one;1-(2-phenylethyl)piperidin-4-one;N-(2-Phenylethyl)-4-Piperidone;1-(2-Phenethyl)-4-Piperidone;N-phenethyl-4-piperidinone;4-Piperidinone, 1-(2-phenylethyl)-;n-phenethyl-4-piperidone;1-(2-Phenylethyl)-4-piperidone;1-(beta-Phenethyl)-4-piperidone;4-Piperidone, 1-phenethyl-;1-(2-Phenylethyl)-4-Piperidinone;NSC 74494;1-(beta-Phenethyl)piperidone;EINECS 254-613-5;UNII-CIS0S4O95K;N-Phenethylpiperidin-4-one;BRN 0130302;CIS0S4O95K;NSC-74494;5-21-06-00425 (Beilstein Handbook Reference);N-(2-Phenethyl)-4-Piperidone;NSC74494;MFCD00006193;phenethylpiperidin-4-one;1-phenylethyl-4-piperidone;1-Phenethyl-4-piperidinone;Oprea1_317085;SCHEMBL486687;1-(.beta.-Phenethyl)piperidone;DTXSID30192826;1-Phenethyl-4-piperidone, 98%;HMS1614L13;N-(2-phenylethyl)-4-piperidinone;BCP22016;1-(.beta.-Phenethyl)-4-piperidone;N-(beta-phenylethyl)-4-piperidinone;4-oxo-1-(2-phenyl-ethyl)-piperidine;AKOS000167639;AC-7234;AM85338;CS-W019878;BP-12535;J83.625G;LS-117278;P1107;SR-01000504718;Q6951396;SR-01000504718-1;W-106406;F8881-6021

This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of 1-Phenethyl-4-piperidone Edit

Chemical Property:

Appearance/Colour:yellow-brown crystalline powder
Vapor Pressure:0.0563mmHg at 25°C
Melting Point:57-60 °C(lit.)
Refractive Index:1.461
Boiling Point:331.1 °C at 760 mmHg
PKA:8.02±0.20(Predicted)
Flash Point:144.2 °C
PSA：20.31000
Density:1.057 g/cm³
LogP:1.83190
Storage Temp.:Store below +30°C.
Solubility.:ethanol: soluble, clear to hazy, light yellow to yellow (50 mg/m
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:203.131014166
Heavy Atom Count:15
Complexity:199

Purity/Quality:

Safty Information:

Pictogram(s): Xn, C, F
Hazard Codes:Xn,C,F
Statements: 22-34-11
Safety Statements: 22-24/25-45-26-36/37/39-16

MSDS Files:: Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1CN(CCC1=O)CCC2=CC=CC=C2
Description 1-phenethyl-4-piperidone is a derivative of 4-piperidinone, being used as an intermediate during the manufacture of chemicals. It is applied for the manufacturing of phenethyl derivative of the propanamide as well as the synthesis of l-Phenethylazacycloheptan-4 -one. It is also used in drugs such as illicitly manufactured nonpharmaceutical fentanyl (NPF) (a potent agonist of opioidreceptors used for anaesthesia and analgesia.
Uses 1-Phenethyl-4-piperidone was used in the preparation of phenethyl derivative of the propanamide. It was also used to synthesize l-Phenethylazacycloheptan-4-one.

Technology Process of 1-Phenethyl-4-piperidone

There total 19 articles about 1-Phenethyl-4-piperidone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 38129-46-3
dimethyl β,β'-(2-phenylethylamino)dipropionate

: 39742-60-4
1-(2-phenylethyl)-4-piperidinone

Guidance literature:: dimethyl β,β'-(2-phenylethylamino)dipropionate; With sodium t-butanolate; In xylene; at 20 ℃; for 24h;

With hydrogenchloride; In water; for 2h; Further stages.; Heating;
DOI:10.1080/00304940809458092