2-{[tert-Butoxy(hydroxy)methylidene]amino}-3-(furan-2-yl)propanoate

Base Information

Chemical Name:2-{[tert-Butoxy(hydroxy)methylidene]amino}-3-(furan-2-yl)propanoate
CAS No.:145206-40-2
Molecular Formula:C12H17NO5
Molecular Weight:436.58
Hs Code.:2932190090
DSSTox Substance ID:DTXSID60932535
Wikidata:Q72449373
Mol file:145206-40-2.mol

Synonyms:DTXSID60932535;2-{[tert-Butoxy(hydroxy)methylidene]amino}-3-(furan-2-yl)propanoate

Suppliers and Price of 2-{[tert-Butoxy(hydroxy)methylidene]amino}-3-(furan-2-yl)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
DicyclohexylAmmonium (S)-2-(tert-butoxycarbonyl-amino)-3-(furan-2-yl)propanoate 95%
1g
$ 422.00

Matrix Scientific
DicyclohexylAmmonium (S)-2-(tert-butoxycarbonyl-amino)-3-(furan-2-yl)propanoate 95%
5g
$ 1266.00

Crysdot
(S)-2-((tert-Butoxycarbonyl)amino)-3-(furan-2-yl)propanoicacid 97%
5g
$ 602.00

Chemenu
(S)-2-((tert-Butoxycarbonyl)amino)-3-(furan-2-yl)propanoicacid 97%
5g
$ 563.00

American Custom Chemicals Corporation
(S)-N-BOC-2-FURYL ALANINE 95.00%
0.5G
$ 183.30

American Custom Chemicals Corporation
(S)-N-BOC-2-FURYL ALANINE 95.00%
1G
$ 764.03

American Custom Chemicals Corporation
(S)-N-BOC-2-FURYL ALANINE 95.00%
5G
$ 1479.56

American Custom Chemicals Corporation
(S)-N-BOC-2-FURYL ALANINE 95.00%
25G
$ 4002.08

AK Scientific
Boc-L-3-(2-Furyl)-alanine
5g
$ 1759.00

Activate Scientific
Boc-3-(2-Furyl)-L-alanine 95% ee
5 g
$ 573.00

Total 36 raw suppliers

Chemical Property of 2-{[tert-Butoxy(hydroxy)methylidene]amino}-3-(furan-2-yl)propanoate

Chemical Property:

Vapor Pressure:1.65E-14mmHg at 25°C
Refractive Index:1.5300 (estimate)
Boiling Point:406.4 °C at 760 mmHg
Flash Point:199.6 °C
PSA：88.77000
Density:1.207 g/cm³
LogP:2.19090
Storage Temp.:2-8°C
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:254.10284761
Heavy Atom Count:18
Complexity:305

Purity/Quality:

97% ^*data from raw suppliers

DicyclohexylAmmonium (S)-2-(tert-butoxycarbonyl-amino)-3-(furan-2-yl)propanoate 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Safety Statements: S24/25:Avoid contact with skin and eyes.;

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC1=CC=CO1)C(=O)[O-]
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CC1=CC=CO1)C(=O)[O-]

Technology Process of 2-{[tert-Butoxy(hydroxy)methylidene]amino}-3-(furan-2-yl)propanoate

There total 14 articles about 2-{[tert-Butoxy(hydroxy)methylidene]amino}-3-(furan-2-yl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 121786-31-0
(S)-2-amino-3-(2-furanyl)propionic acid

: 145206-40-2
(S)-2-t-butoxycarbonylamino-3-furan-2-yl-propionic acid

Guidance literature:: With triethylamine; In methanol; at 60 ℃; for 0.5h;

Reference yield: 46.0%

: 251325-69-6
(2-furan-2-yl-1-hydroxymethyl-ethyl)-carbamic acid tert-butyl ester

: 145206-40-2
(S)-2-t-butoxycarbonylamino-3-furan-2-yl-propionic acid

Guidance literature:: With chromic acid; In diethyl ether; at 20 ℃; for 2h;
DOI:10.1055/s-2005-871944

Reference yield:

: 867193-17-7
4-(2-hydroxy-but-3-enyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

: 145206-40-2
(S)-2-t-butoxycarbonylamino-3-furan-2-yl-propionic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: 52 percent / t-BuOK / dimethylformamide / 18 h / 0 - 20 °C

2.1: Grubbs' catalyst / CH₂Cl₂ / 4 h / 20 °C

2.2: 54 percent / DDQ / benzene / 16 h / Heating

3.1: 82 percent / HCl / methanol / 0.5 h / 0 °C

4.1: 46 percent / aq. H₂CrO₄ / diethyl ether / 2 h / 20 °C

With hydrogenchloride; potassium tert-butylate; chromic acid; Grubbs catalyst first generation; In methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1055/s-2005-871944