4-S-(Hexane-6-ol)sulfidocyclophosphamide

Base Information

Chemical Name:4-S-(Hexane-6-ol)sulfidocyclophosphamide
CAS No.:70396-85-9
Molecular Formula:C13H27 Cl2 N2 O3 P S
Molecular Weight:393.31
Hs Code.:
Mol file:70396-85-9.mol

Synonyms:1-Hexanol,6-[[2-[bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorin-4-yl]thio]-,P-oxide; 2H-1,3,2-Oxazaphosphorine, 1-hexanol deriv.

Suppliers and Price of 4-S-(Hexane-6-ol)sulfidocyclophosphamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-S-(Hexane-6-ol)sulfidocyclophosphamide

Chemical Property:

Vapor Pressure:2.34E-12mmHg at 25°C
Boiling Point:506°C at 760 mmHg
Flash Point:259.8°C
PSA：96.91000
Density:1.28g/cm³
LogP:3.82480

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-S-(Hexane-6-ol)sulfidocyclophosphamide

There total 3 articles about 4-S-(Hexane-6-ol)sulfidocyclophosphamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 50-18-0
cyclophosphamide

: 70396-85-9
6-{2-[bis-(2-chloro-ethyl)-amino]-2-oxo-2λ⁵-[1,3,2]oxazaphosphinan-4-ylsulfanyl}-hexan-1-ol

Guidance literature:: Multi-step reaction with 3 steps

1: (i) O₃, (ii) H₂O₂

2: P(OEt)3

3: CF₃CO₂H

With trifluoroacetic acid; triethyl phosphite;
DOI:10.1016/S0040-4039(01)93578-6

Reference yield:

: 39800-16-3,146566-40-7
4-hydroperoxycyclophosphamide

: 70396-85-9
6-{2-[bis-(2-chloro-ethyl)-amino]-2-oxo-2λ⁵-[1,3,2]oxazaphosphinan-4-ylsulfanyl}-hexan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1: P(OEt)3

2: CF₃CO₂H

With trifluoroacetic acid; triethyl phosphite;
DOI:10.1016/S0040-4039(01)93578-6