(-)-Rubifolide

Base Information

Chemical Name:(-)-Rubifolide
CAS No.:106231-29-2
Molecular Formula:C₂₀H₂₄O₃
Molecular Weight:312.409
Hs Code.:
Mol file:106231-29-2.mol

Synonyms:6,16-Dioxatricyclo[11.2.1.15,8]heptadeca-2,8(17),13,15-tetraen-7-one,3,14-dimethyl-11-(1-methylethenyl)-, [5S-(2Z,5R*,11S*)]-; (+)-Rubifolide;Rubifolide

Suppliers and Price of (-)-Rubifolide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (-)-Rubifolide

Chemical Property:

PSA：39.44000
LogP:4.76180

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (-)-Rubifolide

There total 9 articles about (-)-Rubifolide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 201742-79-2
(-)-bipinnatin J

: 106231-29-2
rubifolide

Guidance literature:: With triethylsilane; trifluoroacetic acid; Inert atmosphere;
DOI:10.1002/anie.200906126

Reference yield: 56.0%

: 1219042-07-5
19-hydroxyrubifolide

: 106231-29-2
rubifolide

Guidance literature:: With triethylsilane; trifluoroacetic acid; In dichloromethane; at 0 ℃;
DOI:10.1016/j.tetlet.2009.12.131

Reference yield:

: 912344-25-3
(S)-3-((E)-5-hydroxy-4-methyl-pent-3-enyl)-5-((Z)-3-iodo-2-methyl-allyl)-5H-furan-2-one

: 106231-29-2
rubifolide

Guidance literature:: Multi-step reaction with 4 steps

1: 92 percent / CyI; CsF / Pd(PPh₃)4 / dimethylformamide

2: 87 percent / PPh₃; NBS

3: 72 percent / CrCl₂; 4 Angstroem molecular sieves / tetrahydrofuran / 16 h / 20 °C

4: 91 percent / Et₃SiH; TFA / CH₂Cl₂ / 0.33 h / 0 °C

With chromium dichloride; triethylsilane; N-Bromosuccinimide; Cyclohexyl iodide; 4 A molecular sieve; triphenylphosphine; cesium fluoride; trifluoroacetic acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; 1: Stille coupling / 2: Appel reaction / 3: Nozaki-Hiyama-Kishi macrocyclization;
DOI:10.1021/ol062581o