5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-[(1E)-2-(2,4-dinitrophenyl)ethenyl]-8-oxo-7-[(2-phenylacetyl)amino]-,(6R,7R)-

Base Information

Chemical Name:5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-[(1E)-2-(2,4-dinitrophenyl)ethenyl]-8-oxo-7-[(2-phenylacetyl)amino]-,(6R,7R)-
CAS No.:163648-72-4
Molecular Formula:C23H18 N4 O8 S
Molecular Weight:510.484
Hs Code.:
Mol file:163648-72-4.mol

Synonyms:5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-[(1E)-2-(2,4-dinitrophenyl)ethenyl]-8-oxo-7-[(phenylacetyl)amino]-,(6R,7R)- (9CI); Cefesone

Suppliers and Price of 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-[(1E)-2-(2,4-dinitrophenyl)ethenyl]-8-oxo-7-[(2-phenylacetyl)amino]-,(6R,7R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-[(1E)-2-(2,4-dinitrophenyl)ethenyl]-8-oxo-7-[(2-phenylacetyl)amino]-,(6R,7R)-

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-[(1E)-2-(2,4-dinitrophenyl)ethenyl]-8-oxo-7-[(2-phenylacetyl)amino]-,(6R,7R)-

There total 2 articles about 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-[(1E)-2-(2,4-dinitrophenyl)ethenyl]-8-oxo-7-[(2-phenylacetyl)amino]-,(6R,7R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 190790-94-4
Tert-butyl-(6R,7R)-3-(2,4-dinitrostyryl)-7-phenylacetamido-ceph-3-em-4-carboxylate

: 163648-72-4
(6R,7R)-3-(2,4-dinitrostyryl)-7-phenylacetamido-ceph-3-em-4-carboxylic acid

Guidance literature:: With titanium tetrachloride; In dichloromethane; at 0 ℃; for 2h;
DOI:10.1016/S0040-4039(97)10857-7

Reference yield:

: (6R,7R)-3-[(E)-2-(2,4-Dinitro-phenyl)-vinyl]-8-oxo-7-phenylacetylamino-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid tert-butyl ester

: 163648-72-4
(6R,7R)-3-(2,4-dinitrostyryl)-7-phenylacetamido-ceph-3-em-4-carboxylic acid

Guidance literature:: With titanium tetrachloride; In dichloromethane; at 0 ℃; for 1.75h; Yield given;
DOI:10.1055/s-1998-2018

Reference yield:

: 163648-72-4
(6R,7R)-3-(2,4-dinitrostyryl)-7-phenylacetamido-ceph-3-em-4-carboxylic acid

: (6R,7R)-7-Amino-3-[(Z)-2-(2,4-dinitro-phenyl)-vinyl]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid

: (6R,7R)-7-Amino-3-[(E)-2-(2,4-dinitro-phenyl)-vinyl]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Guidance literature:: With sodium hydroxide; immobilized penicillin-G acylase; at 32 ℃; for 3h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1055/s-1998-2018