Cicaprost

Base Information

Chemical Name:Cicaprost
CAS No.:95722-07-9
Molecular Formula:C₂₂H₃₀O₅
Molecular Weight:374.477
Hs Code.:
UNII:NE94J8CAMD
DSSTox Substance ID:DTXSID00873211
Nikkaji Number:J398.554G
Wikidata:Q27076013
NCI Thesaurus Code:C174756
Pharos Ligand ID:CC3M6YDXWM9F
ChEMBL ID:CHEMBL160629
Mol file:95722-07-9.mol

Synonyms:13,14-didehydro-16,20-dimethyl-3-oxa-18,18,19,19-tetradehydro-6-carbaprostaglandin I2;5-(7-hydroxy-6-(3-hydroxy-4-methylnona-1,6-diynyl)-bicyclo(3.3.0)octan-3-yliden)-3-oxapentanoic acid;cicaprost;cicaprost dihydrochloride;ZK 96480;ZK-96480

Suppliers and Price of Cicaprost

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of Cicaprost

Chemical Property:

Vapor Pressure:1.94E-16mmHg at 25°C
Boiling Point:591.1°C at 760 mmHg
Flash Point:203.4°C
PSA：86.99000
Density:1.2g/cm³
LogP:2.22490
XLogP3:2.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:374.20932405
Heavy Atom Count:27
Complexity:683

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC#CCC(C)C(C#CC1C(CC2C1CC(=CCOCC(=O)O)C2)O)O
Isomeric SMILES:CCC#CC[C@H](C)[C@@H](C#C[C@H]1[C@@H](C[C@H]2[C@@H]1C/C(=C/COCC(=O)O)/C2)O)O

Technology Process of Cicaprost

There total 30 articles about Cicaprost which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 597557-61-4
(+)-(E,3aS,4S,5R,6aS)-{[5-hydroxy-4-((3S,4S)-3-hydroxy-4-methylnona-1,6-diynyl)-hexahydropentalen-2-yliden]ethoxy}acetic acid tert-butyl ester

: 94079-80-8,95722-07-9
cicaprost

Guidance literature:: With sodium hydroxide; In methanol; at 20 ℃; for 5h;
DOI:10.1021/ja030200l

Reference yield: 86.0%

: 99783-79-6
{2-[(3aS,5R,6aS)-5-(tert-Butyl-dimethyl-silanyloxy)-4-[(3S,4S)-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-nona-1,6-diynyl]-hexahydro-pentalen-(2E)-ylidene]-ethoxy}-acetic acid

: 94079-80-8,95722-07-9
cicaprost

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 25 ℃;
DOI:10.1021/jm00153a001

Reference yield: 86.0%

: 112741-42-1
(1S,5S,6S,7R)-6-(2-bromo-3(S)-hydroxy-4(S)-methyl-1-nonen-6-ynyl)-7-hydroxy-(E)-3-<(4-tert-butoxycarbonyl)-3-oxabutylidene>bicyclo<3.3.0>octane

: 94079-80-8,95722-07-9
cicaprost

Guidance literature:: With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In diethyl ether; toluene; at 55 ℃; for 48h;
DOI:10.1021/jo00241a020