Thiourea, N-(2-(3-propoxyphenyl)ethyl)-N'-2-thiazolyl-

Base Information

• Chemical Name: Thiourea, N-(2-(3-propoxyphenyl)ethyl)-N'-2-thiazolyl-
• CAS No.: 172505-80-5
• Molecular Formula: C15H19N3OS2
• Molecular Weight: 321.4609
• DSSTox Substance ID: DTXSID70169330
• Nikkaji Number: J707.038A
• ChEMBL ID: CHEMBL254415
• Mol file: 172505-80-5.mol

Synonyms:Thiourea, N-(2-(3-propoxyphenyl)ethyl)-N'-2-thiazolyl-;172505-80-5;Thiourea, N-[2-(3-propoxyphenyl)ethyl]-N'-2-thiazolyl-;PETT PrO deriv.;BDBM1907;CHEMBL254415;DTXSID70169330;1-(2-Thiazolyl)-3-[3-propoxyphenethyl]thiourea;1-[2-(3-propoxyphenyl)ethyl]-3-thiazol-2-yl-thiourea;N-(2-(3-Propoxyphenethyl))-N -(2-thiazolyl)thiourea;1-[2-(3-propoxyphenyl)ethyl]-3-1,3-thiazol-2-ylthiourea

Chemical Property of Thiourea, N-(2-(3-propoxyphenyl)ethyl)-N'-2-thiazolyl-

Chemical Property:

• Vapor Pressure: 8.06E-09mmHg at 25°C
• Boiling Point: 464.9°C at 760 mmHg
• Flash Point: 235°C
• Density: 1.255g/cm³
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 321.09695459
• Heavy Atom Count: 21
• Complexity: 317

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCOC1=CC=CC(=C1)CCNC(=S)NC2=NC=CS2

Technology Process of Thiourea, N-(2-(3-propoxyphenyl)ethyl)-N'-2-thiazolyl-

There total 2 articles about Thiourea, N-(2-(3-propoxyphenyl)ethyl)-N'-2-thiazolyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-((E)-2-Nitro-vinyl)-3-propoxy-benzene → 1-[2-(3-Propoxy-phenyl)-ethyl]-3-thiazol-2-yl-thiourea (172505-80-5)

Guidance literature:

Multi-step reaction with 2 steps

1: LAH / tetrahydrofuran

2: acetonitrile / 1 h / 100 °C

With lithium aluminium tetrahydride; In tetrahydrofuran; acetonitrile;

DOI:10.1021/jm00025a010

Reference yield:

2-(3-propyloxyphenyl)ethylamine (103686-13-1) + N-(thiazol-2-yl)-1H-imidazole-1-carbothioamide (149485-85-8) → 1-[2-(3-Propoxy-phenyl)-ethyl]-3-thiazol-2-yl-thiourea (172505-80-5)

Guidance literature:

In acetonitrile; at 100 ℃; for 1h;

DOI:10.1021/jm00025a010

upstream raw materials:

2-(3-propyloxyphenyl)ethylamine

N-(thiazol-2-yl)-1H-imidazole-1-carbothioamide