methyl 2-O-fucopyranosylfucopyranoside 3 sulfate

Base Information

• Chemical Name: methyl 2-O-fucopyranosylfucopyranoside 3 sulfate
• CAS No.: 131511-43-8
• Molecular Formula: C₁₃H₂₃O₁₂S*Na
• Molecular Weight: 426.374
• Mol file: 131511-43-8.mol

Synonyms:methyl 2-O-fucopyranosylfucopyranoside 3 sulfate

Chemical Property of methyl 2-O-fucopyranosylfucopyranoside 3 sulfate

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 192.65000
• Density: g/cm³
• LogP: -2.12260

Purity/Quality:

99% ，98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl 2-O-fucopyranosylfucopyranoside 3 sulfate

There total 8 articles about methyl 2-O-fucopyranosylfucopyranoside 3 sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C34H41O12S(1-)*Na(1+) (131511-42-7) → sodium (methyl 2-O-α-L-fucopyranosyl-α-L-fucopyranoside) 3-sulfate (131511-43-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; for 48h; under 2587.7 Torr; Yield given;

DOI:10.1016/0008-6215(90)80084-G

Reference yield:

(2S,3R,4R,5S,6R)-3,4,5-Tris-benzyloxy-2-methyl-6-methylsulfanyl-tetrahydro-pyran (107802-80-2) → sodium (methyl 2-O-α-L-fucopyranosyl-α-L-fucopyranoside) 3-sulfate (131511-43-8)

Guidance literature:

Multi-step reaction with 7 steps

1: 79 percent / tetrabutylammonium bromide, CuBr₂, molecular sieve 4A / 1,2-dichloro-ethane; dimethylformamide / 16 h / Ambient temperature

2: 70 percent / 60percent aq. acetic acid / 1.5 h / 50 °C

3: 4-toluenesulfonic acid monohydrate / benzene / 1.5 h / Ambient temperature

4: 80percent aq. acetic acid / 1 h / Ambient temperature

5: 79 percent / SO₃-pyridine complex / dimethylformamide / 1.5 h / Ambient temperature

6: 0.1 M sodium methoxide / methanol / 16 h / Ambient temperature

7: H₂ / 10percent Pd-C / aq. ethanol / 48 h / 2587.7 Torr

With pyridine-SO₃ complex; 4 A molecular sieve; p-toluenesulfonic acid monohydrate; tetrabutylammomium bromide; hydrogen; sodium methylate; acetic acid; copper(ll) bromide; palladium on activated charcoal; In methanol; ethanol; 1,2-dichloro-ethane; N,N-dimethyl-formamide; benzene;

DOI:10.1016/0008-6215(90)80084-G

Reference yield:

methyl 3,4-O-isopropylidene-α-L-fucopyranoside → sodium (methyl 2-O-α-L-fucopyranosyl-α-L-fucopyranoside) 3-sulfate (131511-43-8)

Guidance literature:

Multi-step reaction with 7 steps

1: 79 percent / tetrabutylammonium bromide, CuBr₂, molecular sieve 4A / 1,2-dichloro-ethane; dimethylformamide / 16 h / Ambient temperature

2: 70 percent / 60percent aq. acetic acid / 1.5 h / 50 °C

3: 4-toluenesulfonic acid monohydrate / benzene / 1.5 h / Ambient temperature

4: 80percent aq. acetic acid / 1 h / Ambient temperature

5: 79 percent / SO₃-pyridine complex / dimethylformamide / 1.5 h / Ambient temperature

6: 0.1 M sodium methoxide / methanol / 16 h / Ambient temperature

7: H₂ / 10percent Pd-C / aq. ethanol / 48 h / 2587.7 Torr

With pyridine-SO₃ complex; 4 A molecular sieve; p-toluenesulfonic acid monohydrate; tetrabutylammomium bromide; hydrogen; sodium methylate; acetic acid; copper(ll) bromide; palladium on activated charcoal; In methanol; ethanol; 1,2-dichloro-ethane; N,N-dimethyl-formamide; benzene;

DOI:10.1016/0008-6215(90)80084-G

upstream raw materials:

C₃₄H₄₁O₁₂S^(1-)*Na⁽¹⁺⁾

(2S,3R,4R,5S,6R)-3,4,5-Tris-benzyloxy-2-methyl-6-methylsulfanyl-tetrahydro-pyran

methyl 2-O-(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)-α-L-fucopyranoside

methyl 4-O-acetyl-2-O-(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)-α-L-fucopyranoside

Refernces