1-[3-deoxy-3-(5-methyl-1,3,5-dithiazinan-2-yl)-beta-D-arabinofuranosyl]pyrimidine-2,4(1H,3H)-dione

Base Information

Chemical Name:1-[3-deoxy-3-(5-methyl-1,3,5-dithiazinan-2-yl)-beta-D-arabinofuranosyl]pyrimidine-2,4(1H,3H)-dione
CAS No.:130351-52-9
Molecular Formula:C13H19 N3 O5 S2
Molecular Weight:361.4371
Hs Code.:

Synonyms:4H-1,3,5-Dithiazine,2,4(1H,3H)-pyrimidinedione deriv.

Suppliers and Price of 1-[3-deoxy-3-(5-methyl-1,3,5-dithiazinan-2-yl)-beta-D-arabinofuranosyl]pyrimidine-2,4(1H,3H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 1-[3-deoxy-3-(5-methyl-1,3,5-dithiazinan-2-yl)-beta-D-arabinofuranosyl]pyrimidine-2,4(1H,3H)-dione

Chemical Property:

Density:1.512g/cm³

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-[3-deoxy-3-(5-methyl-1,3,5-dithiazinan-2-yl)-beta-D-arabinofuranosyl]pyrimidine-2,4(1H,3H)-dione

There total 2 articles about 1-[3-deoxy-3-(5-methyl-1,3,5-dithiazinan-2-yl)-beta-D-arabinofuranosyl]pyrimidine-2,4(1H,3H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 130351-51-8
1-<3-deoxy-3-C-(4,5-dihydro-5-methyl-1,3,5-dithiazin-2-yl)-5-O-trityl-β-D-arabino-pentofuranosyl>uracil

: 130351-52-9
1-<3-deoxy-3-C-(4,5-dihydro-5-methyl-1,3,5-dithiazin-2-yl)-β-D-arabino-pentofuranosyl>uracil

Guidance literature:: With trifluoroacetic acid; In butan-1-ol; for 0.166667h; Ambient temperature;
DOI:10.1021/jm00171a025

Reference yield:

: 96253-10-0
1-[2,3-epoxy-5-O-(triphenylmethyl)-β-D-lyxofuranosyl]pyrimidine-2,4(1H,3H)-dione

: 130351-52-9
1-<3-deoxy-3-C-(4,5-dihydro-5-methyl-1,3,5-dithiazin-2-yl)-β-D-arabino-pentofuranosyl>uracil

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) hexamethylphosphoramide (HMPA), n-butyllithium / 1.) THF, hexane, -78 deg C, 1 h, 2.) 90 min

2: 90 percent / trifluoroacetic acid / butan-1-ol / 0.17 h / Ambient temperature

With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; trifluoroacetic acid; In butan-1-ol;
DOI:10.1021/jm00171a025