Methylene Blue

Base Information

• Chemical Name: Methylene Blue
• CAS No.: 7220-79-3
• Deprecated CAS: 105504-42-5,121067-62-7,1341-90-8,167498-52-4,6476-03-5,97130-83-1,12262-49-6,1001913-24-1,1001914-35-7,1219638-11-5,923927-02-0,1001913-24-1,1001914-35-7,1219638-11-5,12262-49-6,1341-90-8,152071-32-4,167498-52-4,6476-03-5,923927-02-0,97130-83-1
• Molecular Formula: C16H24ClN3O3S
• Molecular Weight: 373.90
• Hs Code.: 32129000
• European Community (EC) Number: 200-515-2,686-172-3
• NSC Number: 759135,215213,3089,617593
• UNII: 8NAP7826UB
• DSSTox Substance ID: DTXSID0023296
• Wikipedia: Methylene_blue
• Wikidata: Q422134
• NCI Thesaurus Code: C175730
• RXCUI: 2198975
• Pharos Ligand ID: RT814RHG5L5D
• Metabolomics Workbench ID: 152273
• ChEMBL ID: CHEMBL405110
• Mol file: 7220-79-3.mol

Synonyms:basic blue 9;Blue 9, Basic;Blue N, Methylene;Blue, Methylene;Blue, Swiss;Blue, Urolene;Chromosmon;Methylene Blue;Methylene Blue N;Methylthionine Chloride;Methylthioninium Chloride;Swiss Blue;Urolene Blue

Chemical Property of Methylene Blue

Chemical Property:

• Appearance/Colour: Dark green crystalline powder
• Melting Point: 190 °C (dec.)(lit.)
• PKA: 2.6, 11.2(at 25℃)
• Flash Point: 14°C
• PSA: 75.07000
• Density: 0.98 g/mL at 25 °C
• LogP: -0.69000
• Storage Temp.: Store at RT.
• Solubility.: Soluble in water, chloroform; sparingly soluble in ethanol
• Water Solubility.: 4 g/100 mL
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 319.0909965
• Heavy Atom Count: 21
• Complexity: 483

Purity/Quality:

99% ^*data from raw suppliers

Methylene Blue trihydrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn, F
• Hazard Codes: Xn,F
• Statements: 22-36/37/38-11
• Safety Statements: 26-36-24/25-16-7

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Dyes -> Azine Dyes
• Canonical SMILES: CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.[Cl-]
• Recent ClinicalTrials: The Effect of Combination Therapy of Oral MB and PRP-FG in Patients With Non-healing Diabetic Foot Ulcer
• Recent EU Clinical Trials: Photodynamic therapy of antifungal resistant dermatophytes
• Recent NIPH Clinical Trials: Utility comparison test of super -magnifying endoscope for superficial duodenal epithetlial tumors (SDETs)
• Uses: antibacterial Stain in bacteriology; reagent for several chemicals; as mixed indicator; as redox colorimetric agent. Targeting agent for melanoma. Methylene Blue trihydrate finds many uses in biology and chemistry. It acts as a GCS inhibitor, biological stain and redox indicator. It inhibits tau filament formation. Further, it is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes and thus exhibit antimuscarinic effects on IK, ACh and ICa. It also inhibits endothelium-dependent relaxation of isolated blood vessels.