1,3-Bis(2-fluorophenyl)thiourea

Base Information

Chemical Name:1,3-Bis(2-fluorophenyl)thiourea
CAS No.:368-05-8
Molecular Formula:C13H10F2N2S
Molecular Weight:264.2937
Hs Code.:
European Community (EC) Number:665-058-7
NSC Number:51804
DSSTox Substance ID:DTXSID00958012
Nikkaji Number:J658.418G
ChEMBL ID:CHEMBL1316297
Mol file:368-05-8.mol

Synonyms:1,3-bis(2-fluorophenyl)thiourea;368-05-8;N,N'-bis(2-fluorophenyl)thiourea;NSC51804;Maybridge1_007666;MLS001182375;SCHEMBL5449341;CHEMBL1316297;HMS563E10;DTXSID00958012;HMS2881N20;NSC-51804;SEW 04256;1,3-bis(2-fluorophenyl)-2-thiourea;AKOS000669673;SMR000568044;N,N'-Bis(2-fluorophenyl)carbamimidothioic acid;10.14272/ZBMLHTDWAFZBDE-UHFFFAOYSA-N.1;doi:10.14272/ZBMLHTDWAFZBDE-UHFFFAOYSA-N.1

Suppliers and Price of 1,3-Bis(2-fluorophenyl)thiourea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 1,3-Bis(2-fluorophenyl)thiourea

Chemical Property:

Vapor Pressure:0.000126mmHg at 25°C
Boiling Point:334.6°C at 760 mmHg
Flash Point:156.2°C
Density:1.419g/cm³
XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:264.05327583
Heavy Atom Count:18
Complexity:262

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)NC(=S)NC2=CC=CC=C2F)F

Technology Process of 1,3-Bis(2-fluorophenyl)thiourea

There total 5 articles about 1,3-Bis(2-fluorophenyl)thiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.8%

: 348-54-9
2-Fluoroaniline

: 38985-64-7
o-fluorophenyl isothiocyanate

: 368-05-8
sym N,N′-di(2-fluorophenyl)thiourea

Guidance literature:: In ethanol; at 33 - 37 ℃; for 10h;
DOI:10.1002/jhet.2323

Reference yield:

: 348-54-9
2-Fluoroaniline

: 368-05-8
sym N,N′-di(2-fluorophenyl)thiourea

Guidance literature:: Multi-step reaction with 2 steps

1.1: aq. NaOH / Heating

1.2: aq. ethyl chloroformate / Heating

2.1: ethanol / 8 h / 20 °C

With sodium hydroxide; In ethanol;
DOI:10.1016/j.jfluchem.2004.09.002