Pumiliotoxin A

Base Information

Chemical Name:Pumiliotoxin A
CAS No.:67054-00-6
Molecular Formula:C19H33NO2
Molecular Weight:307.475
Hs Code.:
DSSTox Substance ID:DTXSID80897238
Nikkaji Number:J794.478K
Wikidata:Q104396334
ChEMBL ID:CHEMBL145948
Mol file:67054-00-6.mol

Synonyms:alkaloid 307A from Dendrobates;pumiliotoxin A

Suppliers and Price of Pumiliotoxin A

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
PUMILIOTOXIN A 95.00%
5MG
$ 499.15

Total 0 raw suppliers

Chemical Property of Pumiliotoxin A

Chemical Property:

Vapor Pressure:1.93E-09mmHg at 25°C
Boiling Point:436.2°C at 760 mmHg
Flash Point:196.7°C
PSA：43.70000
Density:1.04g/cm³
LogP:3.21320
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:307.251129295
Heavy Atom Count:22
Complexity:443

Purity/Quality:: PUMILIOTOXIN A 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C(=CCC(C)C=C1CC(C2CCCN2C1)(C)O)C)O
Isomeric SMILES:CC[C@@H](/C(=C/C[C@@H](C)/C=C\1/C[C@]([C@@H]2CCCN2C1)(C)O)/C)O

Technology Process of Pumiliotoxin A

There total 36 articles about Pumiliotoxin A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 98088-45-0
(8S,8aS)-8-hydroxy-8-methyl-(6Z)-<(2R,4E,6S)-6-(benzyloxy)-2,5-dimethyl-4-octenylidene>octahydroindolizidine

: 67054-00-6
(+)-pumiliotoxin A

Guidance literature:: With ammonia; lithium; In tetrahydrofuran;
DOI:10.1021/ja961641q

Reference yield: 75.0%

: 98088-45-0
(8S,8aS)-6-[(E)-(S)-6-Benzyloxy-2,5-dimethyl-oct-4-en-(Z)-ylidene]-8-methyl-octahydro-indolizin-8-ol

: 67054-00-6
(+)-pumiliotoxin A

Guidance literature:: With ammonia; lithium; In tetrahydrofuran; at -78 ℃;
DOI:10.1021/jo00219a060

Reference yield: 71.0%

: 251976-94-0
(6Z,8S,8aS)-6-[(2R,4E,6S)-6-(benzyloxy)-2,5-dimethyl-4-octenylidene]-8-{[tert-butyl(dimethyl)silyl]oxy}-8-methyloctahydroindolizine

: 67054-00-6
(+)-pumiliotoxin A

Guidance literature:: (6Z,8S,8aS)-6-[(2R,4E,6S)-6-(benzyloxy)-2,5-dimethyl-4-octenylidene]-8-{[tert-butyl(dimethyl)silyl]oxy}-8-methyloctahydroindolizine; With triethylamine tris(hydrogen fluoride);

With ammonia; lithium; In methanol;
DOI:10.1016/S0022-328X(02)01160-9