3beta-Hydroxylanost-8-en-32-al

Base Information

• Chemical Name: 3beta-Hydroxylanost-8-en-32-al
• CAS No.: 59200-40-7
• Molecular Formula: C₃₀H₅₀O₂
• Molecular Weight: 442.726
• DSSTox Substance ID: DTXSID40974630
• Metabolomics Workbench ID: 34510
• Nikkaji Number: J240.191F
• Wikidata: Q27159344
• Mol file: 59200-40-7.mol

Synonyms:3-beta-hydroxylanost-8-en-32-aldehyde;3-hydroxylanost-8-en-32-al;32-oxo-24,25-dihydrolanosterol;32-oxo-DHL;lanosten-3-ol-32-al;lanosterol-32-aldehyde

Chemical Property of 3beta-Hydroxylanost-8-en-32-al

Chemical Property:

• Vapor Pressure: 4.37E-13mmHg at 25°C
• Boiling Point: 522.2°C at 760 mmHg
• Flash Point: 220.6°C
• PSA: 37.30000
• Density: 1.01g/cm³
• LogP: 7.73800
• XLogP3: 7.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 442.381080833
• Heavy Atom Count: 32
• Complexity: 763

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)CCCC(C)C1CCC2(C1(CCC3=C2CCC4C3(CCC(C4(C)C)O)C)C)C=O
• Isomeric SMILES: C[C@H](CCCC(C)C)[C@H]1CC[C@@]2([C@@]1(CCC3=C2CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)C=O

Technology Process of 3beta-Hydroxylanost-8-en-32-al

There total 8 articles about 3beta-Hydroxylanost-8-en-32-al which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Acetic acid (3S,5R,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-14-formyl-4,4,10,13-tetramethyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester (119318-39-7) → 3β-hydroxylanost-8-en-32-al (59200-40-7)

Guidance literature:

With potassium hydroxide; In methanol; benzene;

DOI:10.1248/cpb.39.1647

Reference yield:

2,2-Dimethyl-propionic acid (3S,5R,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-4,4,10,13-tetramethyl-15-oxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester (130257-83-9) → 3β-hydroxylanost-8-en-32-al (59200-40-7)

Guidance literature:

Multi-step reaction with 5 steps

2: Huang-Minlon reduction

4: 79 percent / pyridinium chlorochromate / CH₂Cl₂

5: 1percent KOH / methanol; benzene

With potassium hydroxide; pyridinium chlorochromate; In methanol; dichloromethane; benzene;

DOI:10.1248/cpb.39.1647

Reference yield:

(3S,5R,10S,13R,14R,17R)-14-Benzyloxymethyl-17-((R)-1,5-dimethyl-hexyl)-3-hydroxy-4,4,10,13-tetramethyl-1,2,3,4,5,6,7,10,11,12,13,14,16,17-tetradecahydro-cyclopenta[a]phenanthren-15-one (136203-69-5) → 3β-hydroxylanost-8-en-32-al (59200-40-7)

Guidance literature:

Multi-step reaction with 4 steps

1: Huang-Minlon reduction

3: 79 percent / pyridinium chlorochromate / CH₂Cl₂

4: 1percent KOH / methanol; benzene

With potassium hydroxide; pyridinium chlorochromate; In methanol; dichloromethane; benzene;

DOI:10.1248/cpb.39.1647

upstream raw materials:

Acetic acid (3S,5R,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-14-formyl-4,4,10,13-tetramethyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester

(5R,10S,13R,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-4,4,10,13-tetramethyl-3-oxo-1,2,3,4,5,6,7,10,11,12,13,15,16,17-tetradecahydro-cyclopenta[a]phenanthrene-14-carbaldehyde

3β-acetoxylanostan-7α-ol

lanost-8-en-3β,32-diol